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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
HCG poses cancer risk
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<blockquote data-quote="JoeMatts" data-source="post: 198119" data-attributes="member: 41444"><p>One of the roles of HCG during pregnancy is to shift the mother's cellular metabolism away from glucose and towards fatty acids - all in order to preserve the former for the developing foetuses brain, as glucose is requite for brain development.</p><p></p><p>One of the hallmarks of cancer - also denoted 'The Warberg Effect' - is the observation that every single cancer cell ever studied lacks the ability to oxidise glucose, instead relying on glycolysis and beta oxidation of fatty acids for energy production. However, many are of the opinion that the Warberg 'effect' is not an effect of cancer, but rather the direct driver of oncogenesis; numerous efficacious cancer drugs are centred around the inhibition of fatty acid synthesis / the promotion of oxidative respiration.</p><p></p><p>Given HCG directly shifts cellular metabolism towards fatty acids, with fatty acids themselves directly promoting glycolysis / inhibiting mitochondrial oxidative phosphorylation via the Randall cycle, there does exist a viable mechanism whereby HCG use could promote cancer.</p><p></p><p>I'm not saying that HCG <em>causes </em>cancer, but this is one of the reasons that I do not use it.</p></blockquote><p></p>
[QUOTE="JoeMatts, post: 198119, member: 41444"] One of the roles of HCG during pregnancy is to shift the mother's cellular metabolism away from glucose and towards fatty acids - all in order to preserve the former for the developing foetuses brain, as glucose is requite for brain development. One of the hallmarks of cancer - also denoted 'The Warberg Effect' - is the observation that every single cancer cell ever studied lacks the ability to oxidise glucose, instead relying on glycolysis and beta oxidation of fatty acids for energy production. However, many are of the opinion that the Warberg 'effect' is not an effect of cancer, but rather the direct driver of oncogenesis; numerous efficacious cancer drugs are centred around the inhibition of fatty acid synthesis / the promotion of oxidative respiration. Given HCG directly shifts cellular metabolism towards fatty acids, with fatty acids themselves directly promoting glycolysis / inhibiting mitochondrial oxidative phosphorylation via the Randall cycle, there does exist a viable mechanism whereby HCG use could promote cancer. I'm not saying that HCG [I]causes [/I]cancer, but this is one of the reasons that I do not use it. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
HCG poses cancer risk
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