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Testosterone Replacement, Low T, HCG, & Beyond
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HCG Mono - Daily Dosage Question
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<blockquote data-quote="zat954" data-source="post: 130083" data-attributes="member: 36336"><p>I am both a new patient to Defy (as of Oct), and am on a high dose of HCG monotherapy. By high dose, I mean 2500iu EOD, with 25mg of Enclomiphene. Before anyone jumps at that dosage, it is important to understand my goal, which in conjunction with Dr. Saya, is regaining fertility at 40 after over a decade of TE overuse/abuse. I am a Functional Medicine practitioner, so I did a great deal of research on all the relevant data before starting this dosage and started on my own for 90 days before presenting both my labs and this Data to Defy.</p><p></p><p>For many years I was not sure I wanted kids, and I have never had issues with any side effects, so my dosage generally kept me over 2000ng/dl TT, 350ng/dl BAT, SHBG 20, and E2 around 45. I never really was bothered by that E level, most likely because my TT/BAT was so high.</p><p></p><p>In June I stopped the TE, and began the regimen above for 90 days, running labs in early Oct.</p><p>My labs after the 90 days, taken just prior to speaking with Dr. S were:</p><p></p><p>TT 1125ng/dl High</p><p>FT 129pg/ml</p><p>LH 1.1 Low</p><p>FSH 4.5</p><p>DHEA 128</p><p>SBGH 48 (in range but too high for my liking)</p><p>E2 10pg/ml VERY LOW</p><p>All other numbers were good.</p><p></p><p>I am 40, 6'2, 210, probably around 12-15%bf</p><p></p><p>A few caveats..... My dose was approved by Defy to be continued based on my research and goals. The literature generally suggests from 1500iu up to 10,000iu 3xWK for people in my situation, with very good success. Also, while my E2 is very low, the logic here is that researchers now believe it is not the HCG dosage itself that downregulates LH receptors, but the E2 dosage.</p><p></p><p>Subjective differences:</p><p>After just over 4 months on this regimen, I notice no real loss of strength or mass, noticeable increase in testicular atrophy, an overall sense of calmness and well being. That said my motivation to train, as well as my libido, are not good. Now this could be a result of the low E2, or it could be due to current stress levels due to school, and the fact I am 4 months out from 10 years of being on SUPERHUMAN test levels, so I am just feeling what a normal 40yo feels. I am considering easing up slightly on the SERM to get E2 up around 20-30. I am very pleased with my TT after only 90 days of HCG, considering how long I was suppressed.</p><p></p><p>Now all that said, once I run a semen analysis next month, I will make adjustments, and once my boys are good I plan to bank enough to start my own army of mini-me's and jump back on T with Dr. Saya's guidance, because I did feel stronger and my libido was better (obviously). I will also stay on a low dose of HCG during so I don't suppress again. I'm not sure what your background or goals are, but make sure you preserve your fertility at all costs if you want kids.</p><p></p><p>Also, I disagree that your labs indicate that your problem is with the testes. That MAY be the case as your LH is high, however with only one lab draw it is hard to know if your T was not previously lower and the body is just now starting to ramp up the LH to get it up. You need multiple labs demonstrating consistently high/normal LH/FSH and low T to know for sure. One snapshot doesn't tell the whole story. Just my 2c, but wanted to let you know HCG monotherapy is and can be done effectively depending on the desired goal. To say its the best option or a long-term option for you or anyone else is debatable and very individualized</p></blockquote><p></p>
[QUOTE="zat954, post: 130083, member: 36336"] I am both a new patient to Defy (as of Oct), and am on a high dose of HCG monotherapy. By high dose, I mean 2500iu EOD, with 25mg of Enclomiphene. Before anyone jumps at that dosage, it is important to understand my goal, which in conjunction with Dr. Saya, is regaining fertility at 40 after over a decade of TE overuse/abuse. I am a Functional Medicine practitioner, so I did a great deal of research on all the relevant data before starting this dosage and started on my own for 90 days before presenting both my labs and this Data to Defy. For many years I was not sure I wanted kids, and I have never had issues with any side effects, so my dosage generally kept me over 2000ng/dl TT, 350ng/dl BAT, SHBG 20, and E2 around 45. I never really was bothered by that E level, most likely because my TT/BAT was so high. In June I stopped the TE, and began the regimen above for 90 days, running labs in early Oct. My labs after the 90 days, taken just prior to speaking with Dr. S were: TT 1125ng/dl High FT 129pg/ml LH 1.1 Low FSH 4.5 DHEA 128 SBGH 48 (in range but too high for my liking) E2 10pg/ml VERY LOW All other numbers were good. I am 40, 6'2, 210, probably around 12-15%bf A few caveats..... My dose was approved by Defy to be continued based on my research and goals. The literature generally suggests from 1500iu up to 10,000iu 3xWK for people in my situation, with very good success. Also, while my E2 is very low, the logic here is that researchers now believe it is not the HCG dosage itself that downregulates LH receptors, but the E2 dosage. Subjective differences: After just over 4 months on this regimen, I notice no real loss of strength or mass, noticeable increase in testicular atrophy, an overall sense of calmness and well being. That said my motivation to train, as well as my libido, are not good. Now this could be a result of the low E2, or it could be due to current stress levels due to school, and the fact I am 4 months out from 10 years of being on SUPERHUMAN test levels, so I am just feeling what a normal 40yo feels. I am considering easing up slightly on the SERM to get E2 up around 20-30. I am very pleased with my TT after only 90 days of HCG, considering how long I was suppressed. Now all that said, once I run a semen analysis next month, I will make adjustments, and once my boys are good I plan to bank enough to start my own army of mini-me's and jump back on T with Dr. Saya's guidance, because I did feel stronger and my libido was better (obviously). I will also stay on a low dose of HCG during so I don't suppress again. I'm not sure what your background or goals are, but make sure you preserve your fertility at all costs if you want kids. Also, I disagree that your labs indicate that your problem is with the testes. That MAY be the case as your LH is high, however with only one lab draw it is hard to know if your T was not previously lower and the body is just now starting to ramp up the LH to get it up. You need multiple labs demonstrating consistently high/normal LH/FSH and low T to know for sure. One snapshot doesn't tell the whole story. Just my 2c, but wanted to let you know HCG monotherapy is and can be done effectively depending on the desired goal. To say its the best option or a long-term option for you or anyone else is debatable and very individualized [/QUOTE]
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HCG Mono - Daily Dosage Question
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