HCG dosage for fertility

Hi all,

I'm about to start TRT with Androgel 1.62% and was prescribed HCG 2x/week at 500 IU each dose to maintain fertility. Is this enough? The sticky mentions a study done by a doctor in Houston that prescribed 500 IU every other day.

Also would there be any difference in taking the 1,000 IU weekly total spread over 2, 3, or 4x/week? I just saw a thread where someone mentioned HCG caused some issues for them and upon stopping they felt better. I'm guessing this has to do with the slight uptick in E2?? If so would spreading the dosage out help? Given I'm in my early 30s and want to retain my fertility I'd like to find an optimum balance.

Also just curious as to what people are paying for HCG want to get an appropriate benchmark
Thanks
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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