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I can super overdose T3 and have no issues. It doesn't even affect my sleep and it takes my LDL way down. The only problem I have is with my thyroid doctor. She gets very upset when I do that :-(. So I'm stuck working with her, which is fine with me. I just changed my dose about 10 weeks ago, I cheated with the first 6. Then went to my proper dose, for Labs on June 4th.