Not sure about transdermal retinol, but my diet is very high in retinol, and I’ve never had an issue with acne regardless of my protocol. I’ve had Test, E2 and dht levels all over the map, and never have issues with acne. Accutane is just high dose synthetic vitamin A. Retinol is just bioavailable vitamin A in the form that ur body prefers, so I would imagine it would have some of the same effects on acne that accutane has
u could also look into progesterone. Most men are low in it while on HRT, and it supposedly helps either inhibit DHT and E2 or balance them out, which I would imagine could help with acne
Here’s a video of a guy that said Calcium d glucarate and DIM both helped get rid of his acne while on HRT
[MEDIA=youtube]0yG8ty_u8XI[/MEDIA]