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Accutane, for all its doom and gloom, is a naturally  occurring derivative of vitamin A.  It’s similar to mega dosing vitamin A .  It didn’t permanently clear my acne but it severely reduced it .  I still get a few pimples here and there but nothing like teenage acne .  It’s also been nearly 20 years since my last dose .  The body also gets rid of the compound rather quickly, within 9 days .