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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Harmonized reference ranges for Total and Free T levels
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<blockquote data-quote="madman" data-source="post: 218718" data-attributes="member: 13851"><p><strong>KEY POINTS </strong></p><p><strong></strong></p><p><strong><em>*Accurate measurement of total testosterone concentrations and, if indicated, free testosterone concentrations is essential for establishing a diagnosis of testosterone deficiency in men </em></strong></p><p><strong><em></em></strong></p><p><strong><em>*Total testosterone concentrations should be measured in the morning in a fasting state using an accurate assay, such as liquid chromatography-tandem mass spectrometry, preferably in a laboratory that is certified by the Centers for Disease Control and Prevention (CDC) Hormone Standardization (HoST) Program for testosterone </em></strong></p><p><strong><em></em></strong></p><p><strong><em>*Free testosterone concentration should be measured in men who are being evaluated for testosterone deficiency when alterations in binding protein concentrations are suspected or when total testosterone concentrations are close to or only slightly below the lower limit of the normal male range</em></strong></p><p><strong><em></em></strong></p><p><strong><em>*Free testosterone concentration preferably should be measured using an equilibrium dialysis method in a reliable laboratory. If an equilibrium dialysis method is not available, free testosterone concentration should be estimated using an equation that has been validated against the equilibrium dialysis method</em></strong></p><p></p><p><em><strong>*Harmonized reference ranges for testosterone concentrations in community-dwelling men have been published and they can be used for assays that have been certified by the CDC’s HoST Program</strong></em></p></blockquote><p></p>
[QUOTE="madman, post: 218718, member: 13851"] [B]KEY POINTS [I]*Accurate measurement of total testosterone concentrations and, if indicated, free testosterone concentrations is essential for establishing a diagnosis of testosterone deficiency in men *Total testosterone concentrations should be measured in the morning in a fasting state using an accurate assay, such as liquid chromatography-tandem mass spectrometry, preferably in a laboratory that is certified by the Centers for Disease Control and Prevention (CDC) Hormone Standardization (HoST) Program for testosterone *Free testosterone concentration should be measured in men who are being evaluated for testosterone deficiency when alterations in binding protein concentrations are suspected or when total testosterone concentrations are close to or only slightly below the lower limit of the normal male range *Free testosterone concentration preferably should be measured using an equilibrium dialysis method in a reliable laboratory. If an equilibrium dialysis method is not available, free testosterone concentration should be estimated using an equation that has been validated against the equilibrium dialysis method[/I][/B] [I][B]*Harmonized reference ranges for testosterone concentrations in community-dwelling men have been published and they can be used for assays that have been certified by the CDC’s HoST Program[/B][/I] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Harmonized reference ranges for Total and Free T levels
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