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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Half Life of Estradiol
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<blockquote data-quote="sbstrum_MD" data-source="post: 97254" data-attributes="member: 17682"><p><strong>Anastrozole DOES lower estradiol (E2)</strong></p><p></p><p></p><p></p><p><span style="color: #0433FF">Arimidex (anastrozole) and exemestane (Aromasin®) are aromatase inhibitors and prevent the metabolism of T → E2. If you have baseline levels of E2 (serum levels easily available via all major labs) that are elevated then you can try either of the two drugs above and then after 1 to 2 weeks recheck your E2 level. I have not heard the term "crashing" your E2. If you are on TRT (testosterone replacement therapy) then it is likely that you will need to be on long term use of an aromatase inhibitor. Once you stop it the T → E2 pathway is again operative. </span></p><p><span style="color: #0433FF">I am not sure of the half-life of E2 in healthy men. In post-menopausal woman getting an estradiol patch, the half-life is 2.7 hours. </span></p><p><span style="color: #0433FF">Lastly, some men are very responsive to aromatase inhibitors and do not require large doses. So the key issues is the context of the patient. In a man using TRT because of hypogonadism, I often see doses of Arimidex as low as 0.5 mg twice a week able to suppress E2 to normal ranges. Hope this helps. </span></p></blockquote><p></p>
[QUOTE="sbstrum_MD, post: 97254, member: 17682"] [b]Anastrozole DOES lower estradiol (E2)[/b] [COLOR=#0433FF][FONT=Helvetica]Arimidex (anastrozole) and exemestane (Aromasin®) are aromatase inhibitors and prevent the metabolism of T → E2. If you have baseline levels of E2 (serum levels easily available via all major labs) that are elevated then you can try either of the two drugs above and then after 1 to 2 weeks recheck your E2 level. I have not heard the term "crashing" your E2. If you are on TRT (testosterone replacement therapy) then it is likely that you will need to be on long term use of an aromatase inhibitor. Once you stop it the T → E2 pathway is again operative. I am not sure of the half-life of E2 in healthy men. In post-menopausal woman getting an estradiol patch, the half-life is 2.7 hours. Lastly, some men are very responsive to aromatase inhibitors and do not require large doses. So the key issues is the context of the patient. In a man using TRT because of hypogonadism, I often see doses of Arimidex as low as 0.5 mg twice a week able to suppress E2 to normal ranges. Hope this helps. [/FONT][/COLOR] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Half Life of Estradiol
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