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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Hair loss
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<blockquote data-quote="Appassionato" data-source="post: 168707" data-attributes="member: 37892"><p>I've discussed it on the thread about hair loss I wrote last week.</p><p>Castrated men after puberty still develop male pattern baldness, even in complete absence of androgens. Men castrated a before puberty don't, as you stated.</p><p></p><p>The huge confusion about the DHT role in hair loss and prostate cancer is that DHT is elevated in the tissues in both cases, not in serum. And, as I said many times, it's because DHT has an anti-inflammatory effect on tissues. Everytime the body senses there's an inflammation, it signals the necessity of an increased concentration of DHT in that tissue.</p><p></p><p>Now, chronic elevation of DHT in the scalp provoke the thinning of blood vessels, also knows as calcification. No blood supply to the scalp = death of the follicles.</p><p>Would you say that DHT is the cause of hair loss then?</p><p>The simplest similitude is what happens with lactic acid accumulation in muscles after a heavy workout. Would you say that lactic acid is the cause of soreness or is it the heavy workout itself?</p><p></p><p>With all that being said, understanding what is causing the inflammation and the epigenetic in play here is quite complicated and could take years.</p><p></p><p>What I would say is to start finding ways to loosen your scalp in the meanwhile, while trying to find the reason behind your hair loss.</p><p>My hairline is basically intact, but I've lost hairs in the crown and mid section of the head, which are the the stiffest sections of my scalp and usually red and itchy.</p></blockquote><p></p>
[QUOTE="Appassionato, post: 168707, member: 37892"] I've discussed it on the thread about hair loss I wrote last week. Castrated men after puberty still develop male pattern baldness, even in complete absence of androgens. Men castrated a before puberty don't, as you stated. The huge confusion about the DHT role in hair loss and prostate cancer is that DHT is elevated in the tissues in both cases, not in serum. And, as I said many times, it's because DHT has an anti-inflammatory effect on tissues. Everytime the body senses there's an inflammation, it signals the necessity of an increased concentration of DHT in that tissue. Now, chronic elevation of DHT in the scalp provoke the thinning of blood vessels, also knows as calcification. No blood supply to the scalp = death of the follicles. Would you say that DHT is the cause of hair loss then? The simplest similitude is what happens with lactic acid accumulation in muscles after a heavy workout. Would you say that lactic acid is the cause of soreness or is it the heavy workout itself? With all that being said, understanding what is causing the inflammation and the epigenetic in play here is quite complicated and could take years. What I would say is to start finding ways to loosen your scalp in the meanwhile, while trying to find the reason behind your hair loss. My hairline is basically intact, but I've lost hairs in the crown and mid section of the head, which are the the stiffest sections of my scalp and usually red and itchy. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Hair loss
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