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General Health & Fitness
Health & Wellness
H. pylori Infection Linked to Metabolic Syndrome
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<blockquote data-quote="Nelson Vergel" data-source="post: 42900" data-attributes="member: 3"><p>[h=3]I truly hate this little bug that has made my life so difficult in the past 3 years.</p><p></p><p>Abstract[/b][h=4]Aim[/b]To systematically review and quantify the effect of <em>Helicobacter pylori</em> (<em>H. pylori</em>) infection on the risk of metabolic syndrome and metabolic parameters in individuals with <em>H. pylori</em> infection.</p><p></p><p></p><p>[h=4]Methods[/b]A systematic search was performed. Inclusion criteria were observational studies assessing association between <em>H. pylori</em> infection and metabolic syndrome in adult participants. We calculated pooled effect estimate of metabolic syndrome with 95% confidence intervals (CI) comparing between group of H. <em>pylori</em> infection and non-infection by using random-effects model. The secondary outcomes were the difference in homeostatic model assessment of insulin resistance (HOMA-IR), triglyceride, high-density lipoprotein (HDL), fasting blood glucose (FBG), body mass index and systolic blood pressure (SBP).</p><p></p><p></p><p>[h=4]Results[/b]Eighteen trials comprising 27,544 participants met the inclusion criteria. Six trials were included in the data analysis of metabolic syndrome. There was a statistically significant association between <em>H. pylori</em> and metabolic syndrome with pooled odds ratio (OR) of 1.34 (95% CI: 1.17 to 1.53, I[SUP]2[/SUP]&#8201;=&#8201;39%, P[SUB]heterogeneity[/SUB]&#8201;<&#8201;0.01). Between the infected and non-infected groups, there were significant differences in FBG, HDL, body mass index, triglyceride, HOMA-IR and SBP (all P&#8201;<&#8201;0.05).</p><p></p><p></p><p>[h=4]Conclusion[/b]<em>H. pylori</em> infection is positively associated with metabolic syndrome. Infection with <em>H. pylori</em> is also associated with higher triglyceride, FBG, body mass index, HOMA-IR, SBP and lower HDL.</p><p><a href="http://www.empr.com/news/h-pylori-infection-linked-to-metabolic-syndrome/article/502665/" target="_blank">http://www.empr.com/news/h-pylori-infection-linked-to-metabolic-syndrome/article/502665/</a></p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 42900, member: 3"] [h=3]I truly hate this little bug that has made my life so difficult in the past 3 years. Abstract[/b][h=4]Aim[/b]To systematically review and quantify the effect of [I]Helicobacter pylori[/I] ([I]H. pylori[/I]) infection on the risk of metabolic syndrome and metabolic parameters in individuals with [I]H. pylori[/I] infection. [h=4]Methods[/b]A systematic search was performed. Inclusion criteria were observational studies assessing association between [I]H. pylori[/I] infection and metabolic syndrome in adult participants. We calculated pooled effect estimate of metabolic syndrome with 95% confidence intervals (CI) comparing between group of H. [I]pylori[/I] infection and non-infection by using random-effects model. The secondary outcomes were the difference in homeostatic model assessment of insulin resistance (HOMA-IR), triglyceride, high-density lipoprotein (HDL), fasting blood glucose (FBG), body mass index and systolic blood pressure (SBP). [h=4]Results[/b]Eighteen trials comprising 27,544 participants met the inclusion criteria. Six trials were included in the data analysis of metabolic syndrome. There was a statistically significant association between [I]H. pylori[/I] and metabolic syndrome with pooled odds ratio (OR) of 1.34 (95% CI: 1.17 to 1.53, I[SUP]2[/SUP] = 39%, P[SUB]heterogeneity[/SUB] < 0.01). Between the infected and non-infected groups, there were significant differences in FBG, HDL, body mass index, triglyceride, HOMA-IR and SBP (all P < 0.05). [h=4]Conclusion[/b][I]H. pylori[/I] infection is positively associated with metabolic syndrome. Infection with [I]H. pylori[/I] is also associated with higher triglyceride, FBG, body mass index, HOMA-IR, SBP and lower HDL. [url]http://www.empr.com/news/h-pylori-infection-linked-to-metabolic-syndrome/article/502665/[/url] [/QUOTE]
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H. pylori Infection Linked to Metabolic Syndrome
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