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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Good e2, high estrone!
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<blockquote data-quote="Cataceous" data-source="post: 220301" data-attributes="member: 38109"><p>This is overstated, and on this point your reference should not be lumping men in with menopausal women. Men continue to rely on the gonads as the primary source of testosterone, a process that is regulated somewhat by serum testosterone, but primarily by serum levels of one of its metabolites: estradiol. A significant fraction of men's estradiol is produced intratesticularly, driven by levels of testosterone and luteinizing hormone. In essence the body is regulating testosterone production to achieve its preferred serum level of estradiol. This belies the idea that serum levels don't matter.</p><p></p><p>If you think serum levels are unimportant then trying injecting 20 mg of estradiol cypionate a week to see what happens. It shouldn't interfere too much with the intracrine processes, but you might discover some of estradiol's endocrine properties.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 220301, member: 38109"] This is overstated, and on this point your reference should not be lumping men in with menopausal women. Men continue to rely on the gonads as the primary source of testosterone, a process that is regulated somewhat by serum testosterone, but primarily by serum levels of one of its metabolites: estradiol. A significant fraction of men's estradiol is produced intratesticularly, driven by levels of testosterone and luteinizing hormone. In essence the body is regulating testosterone production to achieve its preferred serum level of estradiol. This belies the idea that serum levels don't matter. If you think serum levels are unimportant then trying injecting 20 mg of estradiol cypionate a week to see what happens. It shouldn't interfere too much with the intracrine processes, but you might discover some of estradiol's endocrine properties. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Good e2, high estrone!
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