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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Gonadorelin alternative to hCG - Kisspeptin a peptide that is not approved for compounding
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<blockquote data-quote="persevera" data-source="post: 178133" data-attributes="member: 40723"><p>Some compounding pharmacies looked at Gonadorelin as a replacement for HCG in 2008 when they thought compounded HCG was going away due to FDA essential guidance enforcement, thankfully that never happened. Gonadorelin is not a good choice for either testicular volumizing on TRT or as a monotherapy to increase T. It will not stimulate LH unless its timed in specific intervals throughout the day, if this timing is off it will create a paradoxical effect where the LH actually suppresses, therefore, lower T. This is why gonadorelin is never used in urology or male infertility due to its unpredictable results and poor efficacy for this purpose. The same applies to Kisspeptin.</p><p></p><p>Even if Kisspeptin was efficacious, its not listed on the FDA's approved bulks list. This is the list of chemicals US compounders are allowed to compound with. Unfortunately, there are several compounding pharmacies who do not follow the regs and compound unregistered peptides. This fathers everyone's confusion</p></blockquote><p></p>
[QUOTE="persevera, post: 178133, member: 40723"] Some compounding pharmacies looked at Gonadorelin as a replacement for HCG in 2008 when they thought compounded HCG was going away due to FDA essential guidance enforcement, thankfully that never happened. Gonadorelin is not a good choice for either testicular volumizing on TRT or as a monotherapy to increase T. It will not stimulate LH unless its timed in specific intervals throughout the day, if this timing is off it will create a paradoxical effect where the LH actually suppresses, therefore, lower T. This is why gonadorelin is never used in urology or male infertility due to its unpredictable results and poor efficacy for this purpose. The same applies to Kisspeptin. Even if Kisspeptin was efficacious, its not listed on the FDA's approved bulks list. This is the list of chemicals US compounders are allowed to compound with. Unfortunately, there are several compounding pharmacies who do not follow the regs and compound unregistered peptides. This fathers everyone's confusion [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Gonadorelin alternative to hCG - Kisspeptin a peptide that is not approved for compounding
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