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Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
Getting off TRT by Using Enclomiphene
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<blockquote data-quote="Cataceous" data-source="post: 221733" data-attributes="member: 38109"><p>More technically: "Kisspeptin neurons express the estrogen receptor <strong>and the androgen receptor</strong>, and these cells are direct targets for the action of gonadal steroids in both male and female animals. Kisspeptin signaling in the brain has been implicated in mediating the negative feedback action of sex steroids on gonadotropin secretion..."[<a href="https://pubmed.ncbi.nlm.nih.gov/19770291/" target="_blank">R</a>]</p><p></p><p></p><p></p><p>A problem with your experiment is the short time frame. If the pituitary has been shut down for some time then there may be a lag before production of the gonadotropins resumes. In my case it took about a month to see appreciable LH and FSH. I was directly stimulating the pituitary with GnRH, while blocking negative feedback from estradiol with enclomiphene.</p><p></p><p></p><p>That's an average of 8.4 mg of testosterone per day, well over the 6-7 mg produced by the typical young man. The overall normal production range is about 3-9 mg. Nothing low about your dose.</p><p></p><p></p><p>Apparently they are letting a few guys try enclomiphene with TRT to see if any achieve HPTA activity. It was Dr. Saya who had reported seeing no significant HPTA function in several guys who came to him taking Clomid with their TRT.</p><p></p><p></p><p></p><p>You need an LH measurement to see if you actually have HPTA function.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 221733, member: 38109"] More technically: "Kisspeptin neurons express the estrogen receptor [B]and the androgen receptor[/B], and these cells are direct targets for the action of gonadal steroids in both male and female animals. Kisspeptin signaling in the brain has been implicated in mediating the negative feedback action of sex steroids on gonadotropin secretion..."[[URL='https://pubmed.ncbi.nlm.nih.gov/19770291/']R[/URL]] A problem with your experiment is the short time frame. If the pituitary has been shut down for some time then there may be a lag before production of the gonadotropins resumes. In my case it took about a month to see appreciable LH and FSH. I was directly stimulating the pituitary with GnRH, while blocking negative feedback from estradiol with enclomiphene. That's an average of 8.4 mg of testosterone per day, well over the 6-7 mg produced by the typical young man. The overall normal production range is about 3-9 mg. Nothing low about your dose. Apparently they are letting a few guys try enclomiphene with TRT to see if any achieve HPTA activity. It was Dr. Saya who had reported seeing no significant HPTA function in several guys who came to him taking Clomid with their TRT. You need an LH measurement to see if you actually have HPTA function. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
Getting off TRT by Using Enclomiphene
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