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Gene's Nitric Oxide Stack
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<blockquote data-quote="Gene Devine" data-source="post: 2469" data-attributes="member: 4"><p>From a pure research perspective, there's hasn't been much research on it, Paco. Of course there are a lot of good supporting articles on these amino acids that point to their benefits.</p><p></p><p>But remember, the foundation of my stack is the PDE5i Tadalafil and alpha blocker Doxazsin; these are two powerhouses. </p><p></p><p>Everything else is just supplemental and supporting.</p><p></p><p>Good article with good footnotes: <a href="http://www.smart-publications.com/articles/l-citrulline-and-l-arginine-this-one-two-amino-acid-punch-can-improve-" target="_blank">http://www.smart-publications.com/articles/l-citrulline-and-l-arginine-this-one-two-amino-acid-punch-can-improve-</a></p><p></p><p>See the pdf attached. </p><p></p><p><a href="http://www.ncbi.nlm.nih.gov/pubmed/17143054#" target="_blank">Curr Opin Clin Nutr Metab Care.</a> 2007 Jan;10(1):46-51.</p><p><strong>Effects of L-arginine supplementation on exercise metabolism.</strong><a href="http://www.ncbi.nlm.nih.gov/pubmed?term=McConell%20GK%5BAuthor%5D&cauthor=true&cauthor_uid=17143054" target="_blank">McConell GK</a>.</p><p>[h=3]Source[/b]Department of Physiology, The University of Melbourne, Parkville, Victoria, Australia. <a href="mailto:mcconell@unimelb.edu.au">mcconell@unimelb.edu.au</a></p><p></p><p>[h=3]Abstract[/b][h=4]PURPOSE OF REVIEW:[/b]To describe the influence of acute and chronic administration of L-arginine on metabolism at rest and during exercise.</p><p>[h=4]RECENT FINDINGS:[/b]There has been substantial examination of the effect of infusion and ingestion of L-arginine at rest. It has been clearly demonstrated that L-arginine administration improves endothelial function in various disease states. In addition, L-arginine infusion at rest increases plasma insulin, growth hormone, glucagon, catecholamines and prolactin. Such hormonal changes affect metabolism. There has, however, been very little examination of the effect of increases in L-arginine availability during exercise. This is important to study as there is preliminary evidence that L-arginine infusion, probably via increases in nitric oxide (NO), alters skeletal-muscle metabolism during exercise. There is a need for further research, especially to understand the mechanisms of how L-arginine affects exercise metabolism and also to determine whether the hormonal responses that occur in response to L-arginine at rest are also present to some extent during exercise.</p><p>[h=4]SUMMARY:[/b]This line of research may have important therapeutic implications as there are indications that L-arginine augments the effects of exercise training on insulin sensitivity and capillary growth in muscles.</p><p></p><p></p><p>PMID: 17143054 [PubMed - indexed for MEDLINE]</p><p></p><p></p><p>[ATTACH]323[/ATTACH]</p></blockquote><p></p>
[QUOTE="Gene Devine, post: 2469, member: 4"] From a pure research perspective, there's hasn't been much research on it, Paco. Of course there are a lot of good supporting articles on these amino acids that point to their benefits. But remember, the foundation of my stack is the PDE5i Tadalafil and alpha blocker Doxazsin; these are two powerhouses. Everything else is just supplemental and supporting. Good article with good footnotes: [URL]http://www.smart-publications.com/articles/l-citrulline-and-l-arginine-this-one-two-amino-acid-punch-can-improve-[/URL] See the pdf attached. [URL="http://www.ncbi.nlm.nih.gov/pubmed/17143054#"]Curr Opin Clin Nutr Metab Care.[/URL] 2007 Jan;10(1):46-51. [b]Effects of L-arginine supplementation on exercise metabolism.[/b][URL="http://www.ncbi.nlm.nih.gov/pubmed?term=McConell%20GK%5BAuthor%5D&cauthor=true&cauthor_uid=17143054"]McConell GK[/URL]. [h=3]Source[/b]Department of Physiology, The University of Melbourne, Parkville, Victoria, Australia. [email]mcconell@unimelb.edu.au[/email] [h=3]Abstract[/b][h=4]PURPOSE OF REVIEW:[/b]To describe the influence of acute and chronic administration of L-arginine on metabolism at rest and during exercise. [h=4]RECENT FINDINGS:[/b]There has been substantial examination of the effect of infusion and ingestion of L-arginine at rest. It has been clearly demonstrated that L-arginine administration improves endothelial function in various disease states. In addition, L-arginine infusion at rest increases plasma insulin, growth hormone, glucagon, catecholamines and prolactin. Such hormonal changes affect metabolism. There has, however, been very little examination of the effect of increases in L-arginine availability during exercise. This is important to study as there is preliminary evidence that L-arginine infusion, probably via increases in nitric oxide (NO), alters skeletal-muscle metabolism during exercise. There is a need for further research, especially to understand the mechanisms of how L-arginine affects exercise metabolism and also to determine whether the hormonal responses that occur in response to L-arginine at rest are also present to some extent during exercise. [h=4]SUMMARY:[/b]This line of research may have important therapeutic implications as there are indications that L-arginine augments the effects of exercise training on insulin sensitivity and capillary growth in muscles. PMID: 17143054 [PubMed - indexed for MEDLINE] [ATTACH]323[/ATTACH] [/QUOTE]
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