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Gene's Nitric Oxide Stack
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<blockquote data-quote="The Dude" data-source="post: 15230" data-attributes="member: 2592"><p>I expect that supplementation at bedtime affects the body's repair processes during sleep. Supplements that increase blood flow during sleep might help those repair processes. Certainly the ergo-log graph indicates that by perhaps 3am, Citrulline is gone, but at least it was there during the earlier period.</p><p></p><p>Here is an oversimplification of how it works:</p><p></p><p>Nitric Oxide can be generated from Arginine (which in turn can be generated from Citrulline). This method is helped by Korean Red Ginseng or Pycnogenol or Grape Seed Extract or Hawthorn* or Cocoa**, all of which has been shown to inhibit the enzyme that inhibits the production of Nitric Oxide.</p><p></p><p>Nitric Oxide can also be generated from Nitrites which are generated from Nitrates. Nitrates are found in Beets, kale, salads, arugula, etc. This occurs due to an enzyme which can be stimulated with Hawthorn. (this is explained by the following page which also points out that mouthwash can diminish your nitric oxide: <a href="http://theredrushblog.com/2014/05/05/how-red-rush-works-with-bad-illustrations/" target="_blank">http://theredrushblog.com/2014/05/05/how-red-rush-works-with-bad-illustrations/</a> )</p><p></p><p>Nitric Oxide stimulates cGMP production which is what produces all the good effects. cGMP is inhibited by PDE5. PDE5 is inhibited by Sildenafil and Tadalafil and the natural supplement Icariin.</p><p></p><p>The Arginine pathway decreases with age, while the Nitrates one does not, which is why those over 40 are sometimes recommended to use the Nitrate one (Beets and Hawthorn and No Mouthwash) rather than the Arginine one. PDE5 inhibitors should work with both.</p><p></p><p>-----</p><p></p><p>* Note that only Nature's Way Heartcare brand of Hawthorn is standardized for OPCs, the chemical that is similar to Grape Seed, Pycnogenol, etc. (I have no interest in any brand, just what is in the tablets)</p><p></p><p>** The relevant chemicals in Cocoa - Flavonols - are found in Dark Chocolate, not Milk or White chocolate, and Baking Cocoa, but only if not "Dutched" or not "Alkalinized".</p></blockquote><p></p>
[QUOTE="The Dude, post: 15230, member: 2592"] I expect that supplementation at bedtime affects the body's repair processes during sleep. Supplements that increase blood flow during sleep might help those repair processes. Certainly the ergo-log graph indicates that by perhaps 3am, Citrulline is gone, but at least it was there during the earlier period. Here is an oversimplification of how it works: Nitric Oxide can be generated from Arginine (which in turn can be generated from Citrulline). This method is helped by Korean Red Ginseng or Pycnogenol or Grape Seed Extract or Hawthorn* or Cocoa**, all of which has been shown to inhibit the enzyme that inhibits the production of Nitric Oxide. Nitric Oxide can also be generated from Nitrites which are generated from Nitrates. Nitrates are found in Beets, kale, salads, arugula, etc. This occurs due to an enzyme which can be stimulated with Hawthorn. (this is explained by the following page which also points out that mouthwash can diminish your nitric oxide: [URL]http://theredrushblog.com/2014/05/05/how-red-rush-works-with-bad-illustrations/[/URL] ) Nitric Oxide stimulates cGMP production which is what produces all the good effects. cGMP is inhibited by PDE5. PDE5 is inhibited by Sildenafil and Tadalafil and the natural supplement Icariin. The Arginine pathway decreases with age, while the Nitrates one does not, which is why those over 40 are sometimes recommended to use the Nitrate one (Beets and Hawthorn and No Mouthwash) rather than the Arginine one. PDE5 inhibitors should work with both. ----- * Note that only Nature's Way Heartcare brand of Hawthorn is standardized for OPCs, the chemical that is similar to Grape Seed, Pycnogenol, etc. (I have no interest in any brand, just what is in the tablets) ** The relevant chemicals in Cocoa - Flavonols - are found in Dark Chocolate, not Milk or White chocolate, and Baking Cocoa, but only if not "Dutched" or not "Alkalinized". [/QUOTE]
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