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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Gel vs injections
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<blockquote data-quote="Jerajera" data-source="post: 232688" data-attributes="member: 40995"><p>Thanks for replying. I'm pretty sure I posted this somewhere on these forums but when I was on 200mg/day (2 clicks AM and 2 clicks PM) of the compounded cream (I think Empower calls it the HRT base, it wasn't the Atrevis), my DHT at trough (12 hours post injection) was 500ng/dL.</p><p></p><p>What reallly surprised me was that after dropping to half the dose (1 click AM and PM), my DHT was still 360ng/dL. I did feel absolutely amazing for a few days about 1 week after dropping my dose, best I've ever felt in my entire life, but unfortunately quickly went back to feeling just ok.</p><p></p><p>In retrospect I think it might've been from temporary Dopamine receptor resensitization after dropping Test levels, rather than purely a specific hormonal state that I could sustain pretty much forever. Had I been able to sustain that state I would've gladly taken the risk of running 6x the range of DHT levels long term because it was the first time in my life I felt good. But I can't think there aren't any consequences to running insanely high DHT levels for decades on end.</p><p></p><p>I think a lot of people don't understand that just because there aren't any studies showing the negative impact of something, it doesn't mean there is no impact. How does the saying go? Absence of evidence isn't evidence of absence?</p><p></p><p>Interestingly though, libido and EQ were through the roof and my E2 was significantly lower on paper than it had ever been with injections, without accounting for DHT's antagonistic action vs Estrogen at the receptor level.</p></blockquote><p></p>
[QUOTE="Jerajera, post: 232688, member: 40995"] Thanks for replying. I'm pretty sure I posted this somewhere on these forums but when I was on 200mg/day (2 clicks AM and 2 clicks PM) of the compounded cream (I think Empower calls it the HRT base, it wasn't the Atrevis), my DHT at trough (12 hours post injection) was 500ng/dL. What reallly surprised me was that after dropping to half the dose (1 click AM and PM), my DHT was still 360ng/dL. I did feel absolutely amazing for a few days about 1 week after dropping my dose, best I've ever felt in my entire life, but unfortunately quickly went back to feeling just ok. In retrospect I think it might've been from temporary Dopamine receptor resensitization after dropping Test levels, rather than purely a specific hormonal state that I could sustain pretty much forever. Had I been able to sustain that state I would've gladly taken the risk of running 6x the range of DHT levels long term because it was the first time in my life I felt good. But I can't think there aren't any consequences to running insanely high DHT levels for decades on end. I think a lot of people don't understand that just because there aren't any studies showing the negative impact of something, it doesn't mean there is no impact. How does the saying go? Absence of evidence isn't evidence of absence? Interestingly though, libido and EQ were through the roof and my E2 was significantly lower on paper than it had ever been with injections, without accounting for DHT's antagonistic action vs Estrogen at the receptor level. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Gel vs injections
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