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Thyroid, Pregnenolone, Progesterone, DHEA, etc
Thyroid, DHEA, Pregnenolone, Progesterone, etc
FT4 levels on tests and brain fog
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<blockquote data-quote="JoeMatts" data-source="post: 192216" data-attributes="member: 41444"><p>I stopped trt because it made the vast majority of my existing issues worse, as well as contributing various issues of its own. I took it for four years, with bloods and protocol adjustments every twelve weeks, so I gave it plenty of time. The protocol rarely made a difference in how I felt.</p><p></p><p>I don't want to say trt dropping cortisol is common, but I've seen it alot and, from a physiological view, it's almost expected given cortisol and testosterone are inversely related. I'm aware of e2's suppression of T4 -> T3 via upregulation of TBG; my issue was never with conversion, but more so the lack of absolute output from the gland.</p><p></p><p>Testosterone itself is anti-inflammatory, but it's suppression of cortisol would cause my crp and esr to go through the roof — both of which return to normal with cessation. I'll probably try trt again at some point, but only when my thyroid and adrenal issues are solved.</p></blockquote><p></p>
[QUOTE="JoeMatts, post: 192216, member: 41444"] I stopped trt because it made the vast majority of my existing issues worse, as well as contributing various issues of its own. I took it for four years, with bloods and protocol adjustments every twelve weeks, so I gave it plenty of time. The protocol rarely made a difference in how I felt. I don't want to say trt dropping cortisol is common, but I've seen it alot and, from a physiological view, it's almost expected given cortisol and testosterone are inversely related. I'm aware of e2's suppression of T4 -> T3 via upregulation of TBG; my issue was never with conversion, but more so the lack of absolute output from the gland. Testosterone itself is anti-inflammatory, but it's suppression of cortisol would cause my crp and esr to go through the roof — both of which return to normal with cessation. I'll probably try trt again at some point, but only when my thyroid and adrenal issues are solved. [/QUOTE]
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Thyroid, Pregnenolone, Progesterone, DHEA, etc
Thyroid, DHEA, Pregnenolone, Progesterone, etc
FT4 levels on tests and brain fog
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