free vs bioavailable t

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tmckenzie

Member
I have been doing some reading. Seems to me that some are testing for free t, total t, and bioavailable t. I thought free t was the bioavailable. Am I wrong? I have several issues holding me back, e2 is low, prolactin is on higher end, igf was high, now in range but upper end, hgh is high, dht is high. Libido is low, as are other things that trt should help. Was feeling better a while back, but not so much now. So I am wondering about bioavailable t.
 
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Gene Devine

Super Moderator
Free Testosterone = The Testosterone molecule that is not tightly bound to SHBG and loosely Albumin.

Bioavailable Testosterone = The Testosterone molecule that is not tightly bound to SHBG only.

Free and loosely bound Testosterone is what the body will use...that said, even at some point tightly bound becomes available but this is how we measure what the tissues in our body can use.

Low E2 is not healthy and can cause all kinds of sides like low libido and ED.

Prolactin on the higher end coupled with low testosterone could point to a Adenoma especially if LH is on the higher end as well. Higher levels of prolactin will tank libido big time...be aware of that.

High IGF 1 and HGH is a very good thing...you're lucky!

If DHT is high than so would Testosterone.
 

tmckenzie

Member
My endo is really concerned over the high igf and high gh levels. I have empty sella and he suspected an adenoma but could not find it on mri. I use defy for my trt and am waiting to talk with Dr. Saya about the other labs. I have never had bio T checked, they always check free and total. Last check was total 856 and free was 36. e was less than 20. prolactin was 10. I am diabetic but it is in check, adrenal insufficient but cortisol is being replaced, thyroid is being replaced and levels look good. I have taken myself off the small dose of arimidex I was on, but in the past I have not had any libido unless my estradiol was tanked. We never have been able to figure that out. But that was before I knew all my other hormones where out of wack, so maybe I will do better with higher e levels now. It is coming up as nipples are itching this morning some.
 
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