ExcelMale
Menu
Home
What's new
Latest activity
Forums
New posts
Search forums
What's new
New posts
Latest activity
Videos
Lab Tests
Doctor Finder
Buy Books
About Us
Men’s Health Coaching
Log in
Register
What's new
Search
Search
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Navigation
Install the app
Install
More options
Contact us
Close Menu
Forums
Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Free steroid hormones in health and disease (FRESH-HD)
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="madman" data-source="post: 276845" data-attributes="member: 13851"><p>[URL unfurl="true"]https://research.kuleuven.be/portal/en/project/3M240091[/URL]</p><p></p><p>[ATTACH=full]42058[/ATTACH]</p><p></p><p></p><p></p><p></p><p><strong>Project summary</strong></p><p></p><p><em><strong>In routine clinical practice, diagnosis and treatment of endocrine diseases rely mostly on total steroid hormone levels.<u> However, these hormones typically bind to specific proteins and albumin in circulation, with only a small fraction circulating freely</u>. <u>The 'free hormone hypothesis' proposes that this free fraction is responsible for the biological activity of hormones</u>. <u>Unfortunately, measuring free steroid hormone levels is technically challenging, limiting their implementation in clinical practice</u>. In this research project, we aim to enhance the clinical applicability of free steroid hormone concentrations in patients with specific conditions and endocrine diseases, by using <u>state-of-the-art methodology, particularly mass spectrometry, to investigate the clinical relevance of free steroid hormones</u>. The main objectives of this PhD research project will be: - <u>Development, optimization, and validation of methods to measure free steroid hormones - Investigating binding protein-hormone interactions - Studying the interplay between health parameters and free hormones</u>.</strong></em></p></blockquote><p></p>
[QUOTE="madman, post: 276845, member: 13851"] [URL unfurl="true"]https://research.kuleuven.be/portal/en/project/3M240091[/URL] [ATTACH type="full" alt="1709489564730.png"]42058[/ATTACH] [B]Project summary[/B] [I][B]In routine clinical practice, diagnosis and treatment of endocrine diseases rely mostly on total steroid hormone levels.[U] However, these hormones typically bind to specific proteins and albumin in circulation, with only a small fraction circulating freely[/U]. [U]The 'free hormone hypothesis' proposes that this free fraction is responsible for the biological activity of hormones[/U]. [U]Unfortunately, measuring free steroid hormone levels is technically challenging, limiting their implementation in clinical practice[/U]. In this research project, we aim to enhance the clinical applicability of free steroid hormone concentrations in patients with specific conditions and endocrine diseases, by using [U]state-of-the-art methodology, particularly mass spectrometry, to investigate the clinical relevance of free steroid hormones[/U]. The main objectives of this PhD research project will be: - [U]Development, optimization, and validation of methods to measure free steroid hormones - Investigating binding protein-hormone interactions - Studying the interplay between health parameters and free hormones[/U].[/B][/I] [/QUOTE]
Insert quotes…
Verification
Post reply
Share this page
Facebook
Twitter
Reddit
Pinterest
Tumblr
WhatsApp
Email
Share
Link
Sponsors
Forums
Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Free steroid hormones in health and disease (FRESH-HD)
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.
Accept
Learn more…
Top