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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
For those who are struggling on TRT
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<blockquote data-quote="Cataceous" data-source="post: 229724" data-attributes="member: 38109"><p>Our thinking is that the absorption rate of Xyosted is lower than it is with other formulations due to the lack benzyl alcohol. This means a longer effective half-life, but does not imply that any less testosterone is absorbed overall. As you and [USER=38590]@readalot[/USER] note, reporting only trough testosterone measurements is problematic when levels are varying significantly during the injection cycle. A figure of 900 ng/dL does seem reasonable for an average serum TT level when on 100 mg/week of enanthate. My own number is over 1,200 ng/dL. The guys needing 150 mg to reach 700 ng/dL at trough may also have low SHBG, which drives down total testosterone.</p><p></p><p>I'd be more inclined to assign cypionate a nominal half-life of 5 days, based on various information posted by [USER=13851]@madman[/USER]. This makes it little different from enanthate. It is quite a contrast to see a half-life of 10 days reported for Xyosted. This suggests that one needs two injections a week of conventional cypionate or enanthate to be comparable to Xyosted—with respect to the peak and trough levels of serum testosterone.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 229724, member: 38109"] Our thinking is that the absorption rate of Xyosted is lower than it is with other formulations due to the lack benzyl alcohol. This means a longer effective half-life, but does not imply that any less testosterone is absorbed overall. As you and [USER=38590]@readalot[/USER] note, reporting only trough testosterone measurements is problematic when levels are varying significantly during the injection cycle. A figure of 900 ng/dL does seem reasonable for an average serum TT level when on 100 mg/week of enanthate. My own number is over 1,200 ng/dL. The guys needing 150 mg to reach 700 ng/dL at trough may also have low SHBG, which drives down total testosterone. I'd be more inclined to assign cypionate a nominal half-life of 5 days, based on various information posted by [USER=13851]@madman[/USER]. This makes it little different from enanthate. It is quite a contrast to see a half-life of 10 days reported for Xyosted. This suggests that one needs two injections a week of conventional cypionate or enanthate to be comparable to Xyosted—with respect to the peak and trough levels of serum testosterone. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
For those who are struggling on TRT
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