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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
For those who are struggling on TRT
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<blockquote data-quote="Yung4yrs" data-source="post: 228412" data-attributes="member: 44078"><p>Hey Andrew, here's some stuff for you to add to your "rethink".</p><p></p><p>1) 5-7 mg per day adult guy is the kinda standard thing on T production. BUT, if the NIH acted in a truly even-handed, non-feminized, non-PC fashion, the fact that in general testosterone levels have on average been dropping 10% per decade for the last 60 years would be declared a public health emergency.</p><p></p><p>April, 1999, Journal of Behavioral Medicine</p><p>4,393 men between 32 & 44, AVG total testosterone = 679 ng/dl</p><p>Range of actual draws: 53-1500; the study's statistically normal range: 270-1070</p><p></p><p>This means that 23 yrs ago close to half the male population your age was walking around and considered normal with a total T of 700-1100. Docs today consider 600-800 "normal" because it is the statistical mean after 60 years of American guys losing 10% per decade of their normal T.</p><p></p><p>Now again this was 23 yrs ago and guys 32-44 yrs old. Not 19 yr old teens. I might guess that in 1962 instead of 2022, half the 19 yr old teens may have been walking around with T between 1000 and 1500. I graduated HS in 1970. It sure felt like it then. <img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite1" alt=":)" title="Smile :)" loading="lazy" data-shortname=":)" /></p><p></p><p>2) Guys constantly talk about how many mg's of T. But rarely do I see the differentiation between a testosterone preparation and actual raw T. T Cypionate for example is by weight only 65% T. The other 35% is the ester attached to the T molecule that gives it the "slo-release" property. So for example, 100mg of T Cyp yields 65mg of Testosterone USP.</p><p></p><p>3) If a guy IM injects 200 mg T Cyp once weekly into into his glute, as the ester releases the T at the injection site the guy gets 130mg released into the muscle tissue of his back side. How much usable hormone actually ends up in bloodstream? As a practical matter, this is what the blood tests are for. I don't think though it's 100%.</p><p></p><p>So my opinion is guys wanting to run an avg of say 700 to 1000 aren't "out of line", but rather may have been completely avg normal the day I graduated from high school. I say, "What's the matter with that?"</p></blockquote><p></p>
[QUOTE="Yung4yrs, post: 228412, member: 44078"] Hey Andrew, here's some stuff for you to add to your "rethink". 1) 5-7 mg per day adult guy is the kinda standard thing on T production. BUT, if the NIH acted in a truly even-handed, non-feminized, non-PC fashion, the fact that in general testosterone levels have on average been dropping 10% per decade for the last 60 years would be declared a public health emergency. April, 1999, Journal of Behavioral Medicine 4,393 men between 32 & 44, AVG total testosterone = 679 ng/dl Range of actual draws: 53-1500; the study's statistically normal range: 270-1070 This means that 23 yrs ago close to half the male population your age was walking around and considered normal with a total T of 700-1100. Docs today consider 600-800 "normal" because it is the statistical mean after 60 years of American guys losing 10% per decade of their normal T. Now again this was 23 yrs ago and guys 32-44 yrs old. Not 19 yr old teens. I might guess that in 1962 instead of 2022, half the 19 yr old teens may have been walking around with T between 1000 and 1500. I graduated HS in 1970. It sure felt like it then. :) 2) Guys constantly talk about how many mg's of T. But rarely do I see the differentiation between a testosterone preparation and actual raw T. T Cypionate for example is by weight only 65% T. The other 35% is the ester attached to the T molecule that gives it the "slo-release" property. So for example, 100mg of T Cyp yields 65mg of Testosterone USP. 3) If a guy IM injects 200 mg T Cyp once weekly into into his glute, as the ester releases the T at the injection site the guy gets 130mg released into the muscle tissue of his back side. How much usable hormone actually ends up in bloodstream? As a practical matter, this is what the blood tests are for. I don't think though it's 100%. So my opinion is guys wanting to run an avg of say 700 to 1000 aren't "out of line", but rather may have been completely avg normal the day I graduated from high school. I say, "What's the matter with that?" [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
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