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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
For Those That Get Headaches on TRT
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<blockquote data-quote="Fortunate" data-source="post: 268291" data-attributes="member: 42264"><p>Anyone around here that has read any of my posts knows that the biggest thing that stands between me and achieving therapeutic HRT benefit is <u>headache</u>. [USER=38594]@sammmy[/USER], or anyone else that has contemplated headache, <strong>what are your thoughts on histamine as a potential cause or contributory factor?</strong></p><p></p><p>I have systematically tried to isolate the source of the headaches. I have made a number of observations over the course of time, but won't bore you with the details. A few salient observations: </p><ul> <li data-xf-list-type="ul">Even tiny doses of injected esters cause headaches<ul> <li data-xf-list-type="ul">therefore, seems unlikely that hormone levels are the culprit</li> </ul></li> <li data-xf-list-type="ul">Xyosted is less likely to cause a headache (but this is not always true)<ul> <li data-xf-list-type="ul">suggests that preservatives and/or alcohol could be a culprit or contributors to the headache pathway</li> </ul></li> <li data-xf-list-type="ul">Yogurt triggers headaches (even unsweetened, plain Greek)<ul> <li data-xf-list-type="ul">makes me wonder if I am sensitive to histamine triggering things</li> </ul></li> <li data-xf-list-type="ul">Verapamil has helped control my headaches in the past<ul> <li data-xf-list-type="ul">making it seem more likely that one pathway to headache for me is vascular<ul> <li data-xf-list-type="ul">maybe verapamil promotes vascular relaxation or dilatation (or, instead, simply keeps vasculature stable)</li> </ul></li> </ul></li> <li data-xf-list-type="ul">Anything with pseudoephedrine causes bad headache hours after taking it<ul> <li data-xf-list-type="ul">Very much suspect this is due to vasoconstriction or vasospasm or vasorelaxation after a state of constriction, suggesting that I am likely sensitive to vascular events </li> </ul></li> <li data-xf-list-type="ul">Triptans work well for me<ul> <li data-xf-list-type="ul">one theory on triptans is that they may influence neurovasculature</li> </ul></li> </ul><p>Based on various observations, I suspect that injections trigger some kind of vascular response - either directly or via something like histamine? I have considered various possibilities (oil, preservative, excipient) and have tried to test all of them (I can provide details if interested).</p><p></p><p>I have never tried taking Benadryl along with an injection, but may consider it. On the other hand, I don't want to fall asleep every time I inject....</p><p></p><p>Any thoughts?</p></blockquote><p></p>
[QUOTE="Fortunate, post: 268291, member: 42264"] Anyone around here that has read any of my posts knows that the biggest thing that stands between me and achieving therapeutic HRT benefit is [U]headache[/U]. [USER=38594]@sammmy[/USER], or anyone else that has contemplated headache, [B]what are your thoughts on histamine as a potential cause or contributory factor?[/B] I have systematically tried to isolate the source of the headaches. I have made a number of observations over the course of time, but won't bore you with the details. A few salient observations: [LIST] [*]Even tiny doses of injected esters cause headaches [LIST] [*]therefore, seems unlikely that hormone levels are the culprit [/LIST] [*]Xyosted is less likely to cause a headache (but this is not always true) [LIST] [*]suggests that preservatives and/or alcohol could be a culprit or contributors to the headache pathway [/LIST] [*]Yogurt triggers headaches (even unsweetened, plain Greek) [LIST] [*]makes me wonder if I am sensitive to histamine triggering things [/LIST] [*]Verapamil has helped control my headaches in the past [LIST] [*]making it seem more likely that one pathway to headache for me is vascular [LIST] [*]maybe verapamil promotes vascular relaxation or dilatation (or, instead, simply keeps vasculature stable) [/LIST] [/LIST] [*]Anything with pseudoephedrine causes bad headache hours after taking it [LIST] [*]Very much suspect this is due to vasoconstriction or vasospasm or vasorelaxation after a state of constriction, suggesting that I am likely sensitive to vascular events [/LIST] [*]Triptans work well for me [LIST] [*]one theory on triptans is that they may influence neurovasculature [/LIST] [/LIST] Based on various observations, I suspect that injections trigger some kind of vascular response - either directly or via something like histamine? I have considered various possibilities (oil, preservative, excipient) and have tried to test all of them (I can provide details if interested). I have never tried taking Benadryl along with an injection, but may consider it. On the other hand, I don't want to fall asleep every time I inject.... Any thoughts? [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
For Those That Get Headaches on TRT
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