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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
For Those That Get Headaches on TRT
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<blockquote data-quote="madman" data-source="post: 234477" data-attributes="member: 13851"><p>Far fetched!</p><p></p><p></p><p></p><p></p><p><strong>Pharmacokinetics of testosterone cream applied to scrotal skin (2017)</strong></p><p><strong></strong></p><p><strong></strong></p><p><strong><em>*After testosterone administration, the peak concentration of serum testosterone was dose-dependent with the time of peak being between 1.9 to 2.8 h after doses (Table 2).</em></strong></p><p><strong><em>[ATTACH=full]25894[/ATTACH]</em></strong></p><p><strong><em>[ATTACH=full]25895[/ATTACH]</em></strong></p><p><strong></strong></p><p><strong></strong></p><p><strong></strong></p><p><strong></strong></p><p><strong>A New Oral Testosterone Undecanoate Formulation Restores Testosterone to Normal Concentrations in Hypogonadal Men (2020)</strong></p><p></p><p></p><p><em><strong>*When the T results of all patients at a particular visit were combined, regardless of the dose of oral TU they received, the mean peak T over 24 hrs. (Cmax24) for oral </strong></em><strong><em>TU patients ranged from approximately 800 ng/dL at the first dose titration to 1000 ng/dL at the end of the study and occurred at <u>median times of approximately 2–4 hours following the AM dose and approximately 4 hours following the PM dose</u></em></strong></p><p><strong><em>[ATTACH=full]25896[/ATTACH]</em></strong></p><p><strong><em>[ATTACH=full]25897[/ATTACH]</em></strong></p><p></p><p></p><p></p><p></p><p></p><p>Natesto takes the cake when it comes to Tmax!</p><p></p><p>[ATTACH=full]25901[/ATTACH]</p><p>[ATTACH=full]25902[/ATTACH]</p><p></p><p></p><p><strong>12.3. Pharmacokinetics Absorption </strong></p><p></p><p><em>Natesto delivers physiologic amounts of testosterone, producing circulating concentrations that approximate normal testosterone concentrations (i.e., 300 to 1,050 ng/dL) seen in healthy men. <strong>The maximum concentration for Natesto is achieved within approximately 40 minutes of administration and has a half-life ranging from 10 to 100 minutes. </strong>Figure 1 summarizes the pharmacokinetic profiles of total testosterone in patients completing 90 days of Natesto treatment administered as 33 mg of testosterone daily (11 mg three times daily).</em></p><p></p><p></p><p><strong>Figure 1: Mean Serum Total Testosterone Concentrations on Day 90 Following Natesto Administered As 11 mg of Testosterone Three Times Daily (N=69)</strong></p><p><strong>[ATTACH=full]25898[/ATTACH]</strong></p></blockquote><p></p>
[QUOTE="madman, post: 234477, member: 13851"] Far fetched! [B]Pharmacokinetics of testosterone cream applied to scrotal skin (2017) [I]*After testosterone administration, the peak concentration of serum testosterone was dose-dependent with the time of peak being between 1.9 to 2.8 h after doses (Table 2). [ATTACH type="full" alt="Screenshot (17713).png"]25894[/ATTACH] [ATTACH type="full" alt="Screenshot (17714).png"]25895[/ATTACH][/I] A New Oral Testosterone Undecanoate Formulation Restores Testosterone to Normal Concentrations in Hypogonadal Men (2020)[/B] [I][B]*When the T results of all patients at a particular visit were combined, regardless of the dose of oral TU they received, the mean peak T over 24 hrs. (Cmax24) for oral [/B][/I][B][I]TU patients ranged from approximately 800 ng/dL at the first dose titration to 1000 ng/dL at the end of the study and occurred at [U]median times of approximately 2–4 hours following the AM dose and approximately 4 hours following the PM dose[/U] [ATTACH type="full" alt="Screenshot (17715).png"]25896[/ATTACH] [ATTACH type="full" alt="Screenshot (17716).png"]25897[/ATTACH][/I][/B] Natesto takes the cake when it comes to Tmax! [ATTACH type="full" alt="Screenshot (17720).png"]25901[/ATTACH] [ATTACH type="full" alt="Screenshot (17721).png"]25902[/ATTACH] [B]12.3. Pharmacokinetics Absorption [/B] [I]Natesto delivers physiologic amounts of testosterone, producing circulating concentrations that approximate normal testosterone concentrations (i.e., 300 to 1,050 ng/dL) seen in healthy men. [B]The maximum concentration for Natesto is achieved within approximately 40 minutes of administration and has a half-life ranging from 10 to 100 minutes. [/B]Figure 1 summarizes the pharmacokinetic profiles of total testosterone in patients completing 90 days of Natesto treatment administered as 33 mg of testosterone daily (11 mg three times daily).[/I] [B]Figure 1: Mean Serum Total Testosterone Concentrations on Day 90 Following Natesto Administered As 11 mg of Testosterone Three Times Daily (N=69) [ATTACH type="full" alt="Screenshot (17717).png"]25898[/ATTACH][/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
For Those That Get Headaches on TRT
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