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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Following Up- Blood tesf results. 28M
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<blockquote data-quote="jcmaxwell" data-source="post: 181556" data-attributes="member: 38456"><p>Before you make any decision to begin treatment at age 28, you need to run a valid free Testosterone (fT) test. The gold standard is the Equilibrium Dialysis assay; another alternative is Equilibrium Ultrafiltration, which is less expensive but correlates very well with Equilibrium Dialysis. The fT test ordered by Defy is the inexpensive Direct Immunoassay test, which has been discredited by top researchers. It is known to be completely inaccurate and does not correlate with any other testosterone test. (You could be mid-range on an Equilibrium Dialysis assay but 20 percent below the low end reference range on a Direct Immunoassay test.) I recently posted the following:</p><p></p><p>"In fact, Direct Immunoassay fT has been completed discredited over the last 20 years. William Rosner wrote a scathing Letter to the Editor (July 2001, Journal of Endocrinology and Metabolism) entitled, 'An Extraordinarily Inaccurate Assay for Free Testosterone is Still with Us'. He cited the work of Vermeulen and others demonstrating that Direct Immunoassay fT '<span style="color: rgb(184, 49, 47)">is seriously inaccurate, underestimating its concentration by <strong>many-fold</strong>.'"</span></p></blockquote><p></p>
[QUOTE="jcmaxwell, post: 181556, member: 38456"] Before you make any decision to begin treatment at age 28, you need to run a valid free Testosterone (fT) test. The gold standard is the Equilibrium Dialysis assay; another alternative is Equilibrium Ultrafiltration, which is less expensive but correlates very well with Equilibrium Dialysis. The fT test ordered by Defy is the inexpensive Direct Immunoassay test, which has been discredited by top researchers. It is known to be completely inaccurate and does not correlate with any other testosterone test. (You could be mid-range on an Equilibrium Dialysis assay but 20 percent below the low end reference range on a Direct Immunoassay test.) I recently posted the following: "In fact, Direct Immunoassay fT has been completed discredited over the last 20 years. William Rosner wrote a scathing Letter to the Editor (July 2001, Journal of Endocrinology and Metabolism) entitled, 'An Extraordinarily Inaccurate Assay for Free Testosterone is Still with Us'. He cited the work of Vermeulen and others demonstrating that Direct Immunoassay fT '[COLOR=rgb(184, 49, 47)]is seriously inaccurate, underestimating its concentration by [B]many-fold[/B].'"[/COLOR] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Following Up- Blood tesf results. 28M
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