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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
First labs since starting TRT - very surprised by results!
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<blockquote data-quote="madman" data-source="post: 188566" data-attributes="member: 13851"><p>This would be expected when injecting once weekly as levels will peak (8-12 hr) post-injection and be elevated the first few days only to be followed by much lower levels come weeks end which can have a negative impact on energy/mood/libido/erectile function/recovery.</p><p></p><p>In your case, trough FT levels were still through the roof 7 days post-injection so your levels are still very robust come weeks end before your next injection which would mean that the down and out feeling you were experiencing would most likely be due to the extreme fluctuation in your peak--->trough levels as your peak TT/FT/e2 levels will be much higher post-injection/days following.</p><p></p><p>Injecting 50 mg every 3.5 days (keeping overall weekly dose @100 mg/week) will most likely still allow you to achieve a healthy FT level as not only will you be clipping the peak--->trough but your blood levels will be more stable throughout the week.</p><p></p><p>The only way you will know where your trough TT/FT/e2 levels truly sit is to stay consistent with your new protocol (dose T/injection frequency) and once levels have stabilized (4-6 weeks) then get blood work done.</p><p></p><p>Again forget worrying about where your trough TT will end up on such protocol as FT is what you want to pay attention to let alone SHBG, estradiol.</p><p></p><p>Testing needs to be done using accurate assays for TT (LC-MS/MS), FT (Equilibrium Dialysis or Ultrafiltration), and estradiol (LC-MS/MS).</p><p></p><p>Your doctor used #2 on your last set of labs.</p><p></p><p>Any of the 3 below will suffice.</p><p></p><p>Everyone on trt should be using these assays to test Free Testosterone!</p><p></p><p></p><p></p><p></p><p><span style="color: rgb(184, 49, 47)"><strong>1</strong></span> <a href="https://www.labcorp.com/tests/500726/testosterone-free-mass-spectrometry-equilibrium-dialysis-endocrine-sciences" target="_blank">500726: Testosterone, Free, Mass Spectrometry/Equilibrium Dialysis (Endocrine Sciences) | LabCorp</a></p><p></p><p><span style="color: rgb(184, 49, 47)"><strong>2</strong></span> <a href="https://www.labcorp.com/tests/081786/testosterone-free-equilibrium-ultrafiltration-with-total-testosterone" target="_blank">081786: Testosterone, Free, Equilibrium Ultrafiltration With Total Testosterone | LabCorp</a></p><p></p><p><span style="color: rgb(184, 49, 47)"><strong>3</strong></span> <a href="https://www.discountedlabs.com/hematocrit-total-and-free-testosterone-1500-ng-dl" target="_blank">Testosterone, Total and Free (NO Upper Limit) plus Hematocrit</a></p></blockquote><p></p>
[QUOTE="madman, post: 188566, member: 13851"] This would be expected when injecting once weekly as levels will peak (8-12 hr) post-injection and be elevated the first few days only to be followed by much lower levels come weeks end which can have a negative impact on energy/mood/libido/erectile function/recovery. In your case, trough FT levels were still through the roof 7 days post-injection so your levels are still very robust come weeks end before your next injection which would mean that the down and out feeling you were experiencing would most likely be due to the extreme fluctuation in your peak--->trough levels as your peak TT/FT/e2 levels will be much higher post-injection/days following. Injecting 50 mg every 3.5 days (keeping overall weekly dose @100 mg/week) will most likely still allow you to achieve a healthy FT level as not only will you be clipping the peak--->trough but your blood levels will be more stable throughout the week. The only way you will know where your trough TT/FT/e2 levels truly sit is to stay consistent with your new protocol (dose T/injection frequency) and once levels have stabilized (4-6 weeks) then get blood work done. Again forget worrying about where your trough TT will end up on such protocol as FT is what you want to pay attention to let alone SHBG, estradiol. Testing needs to be done using accurate assays for TT (LC-MS/MS), FT (Equilibrium Dialysis or Ultrafiltration), and estradiol (LC-MS/MS). Your doctor used #2 on your last set of labs. Any of the 3 below will suffice. Everyone on trt should be using these assays to test Free Testosterone! [COLOR=rgb(184, 49, 47)][B]1[/B][/COLOR] [URL='https://www.labcorp.com/tests/500726/testosterone-free-mass-spectrometry-equilibrium-dialysis-endocrine-sciences']500726: Testosterone, Free, Mass Spectrometry/Equilibrium Dialysis (Endocrine Sciences) | LabCorp[/URL] [COLOR=rgb(184, 49, 47)][B]2[/B][/COLOR] [URL='https://www.labcorp.com/tests/081786/testosterone-free-equilibrium-ultrafiltration-with-total-testosterone']081786: Testosterone, Free, Equilibrium Ultrafiltration With Total Testosterone | LabCorp[/URL] [COLOR=rgb(184, 49, 47)][B]3[/B][/COLOR] [URL='https://www.discountedlabs.com/hematocrit-total-and-free-testosterone-1500-ng-dl']Testosterone, Total and Free (NO Upper Limit) plus Hematocrit[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
First labs since starting TRT - very surprised by results!
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