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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
First blood work after adding Nandrolone
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<blockquote data-quote="madman" data-source="post: 197184" data-attributes="member: 13851"><p>[URL unfurl="true"]https://www.labcorp.com/tests/081786/testosterone-free-equilibrium-ultrafiltration-with-total-testosterone[/URL]</p><p></p><p><strong>Testosterone, Free, Equilibrium Ultrafiltration With Total Testosterone</strong></p><p><strong></strong></p><p><strong>TEST: 081786</strong></p><p><strong></strong></p><p><strong></strong></p><p><strong>Methodology</strong></p><p><strong><em>Free:</em></strong> equilibrium ultrafiltration; <strong><em>total:</em></strong> <u>electrochemiluminescence immunoassay (ECLIA)</u></p><p></p><p></p><p></p><p></p><p></p><p></p><p><strong>Elecsys Testosterone II cobas®</strong></p><p><strong></strong></p><p><strong></strong></p><p><strong>English </strong></p><p><strong></strong></p><p><strong>System information</strong></p><p>For cobas e 411 analyzer: test number 111 For MODULAR ANALYTICS E170, cobas e 601 and cobas e 602 analyzers: Application Code Number 216</p><p></p><p><strong>Intended use</strong></p><p>Immunoassay for the in vitro quantitative determination of testosterone in human serum and plasma.</p><p></p><p><strong>The <u>electrochemiluminescence immunoassay “ECLIA” is intended for use on Elecsys and cobas e immunoassay analyzers</u>.</strong></p><p><strong></strong></p><p><strong></strong></p><p><strong></strong></p><p><strong>Limitations - interference</strong></p><p></p><p>The assay is unaffected by icterus (bilirubin < 513 µmol/L or < 30 mg/dL), hemolysis (Hb < 0.372 mmol/L or < 0.600 g/dL), lipemia (Intralipid < 1000 mg/dL) and biotin (< 123 nmol/L or < 30 ng/mL).</p><p></p><p>Criterion: Recovery within ± 10 % of initial value (concentration range > 1‑15 ng/mL), recovery within ± 15 % of initial value (concentration range > 0.5‑1 ng/mL) and recovery of ± 0.075 ng/mL (concentration range of 0.150‑0.500 ng/mL).</p><p></p><p>Samples should not be taken from patients receiving therapy with high biotin doses (i.e. > 5 mg/day) until at least 8 hours following the last biotin administration.</p><p></p><p>No interference was observed from rheumatoid factors up to a concentration of 1000 IU/mL.</p><p></p><p>In vitro tests were performed on 18 commonly used pharmaceuticals. No interference with the assay was found.</p><p></p><p>Two special drugs were additionally tested. <strong><u>Strong interaction with Nandrolone (INN international nonproprietary name, WHO) was found. Do not use samples from patients under Nandrolone treatment</u>. </strong></p><p></p><p>In isolated cases, elevated testosterone levels can be seen in samples from female patients with end-stage renal disease (ESRD).</p><p></p><p>Implausible elevated testosterone values in women should be verified by an extraction method or a validated LC‑MS/MS tandem method.5</p><p></p><p>In rare cases, interference due to extremely high titers of antibodies to analyte‑specific antibodies, streptavidin, or ruthenium can occur. These effects are minimized by a suitable test design.</p><p></p><p>For diagnostic purposes, the results should always be assessed in conjunction with the patient’s medical history, clinical examination, and other findings.</p></blockquote><p></p>
[QUOTE="madman, post: 197184, member: 13851"] [URL unfurl="true"]https://www.labcorp.com/tests/081786/testosterone-free-equilibrium-ultrafiltration-with-total-testosterone[/URL] [B]Testosterone, Free, Equilibrium Ultrafiltration With Total Testosterone TEST: 081786 Methodology [I]Free:[/I][/B] equilibrium ultrafiltration; [B][I]total:[/I][/B] [U]electrochemiluminescence immunoassay (ECLIA)[/U] [B]Elecsys Testosterone II cobas® English System information[/B] For cobas e 411 analyzer: test number 111 For MODULAR ANALYTICS E170, cobas e 601 and cobas e 602 analyzers: Application Code Number 216 [B]Intended use[/B] Immunoassay for the in vitro quantitative determination of testosterone in human serum and plasma. [B]The [U]electrochemiluminescence immunoassay “ECLIA” is intended for use on Elecsys and cobas e immunoassay analyzers[/U]. Limitations - interference[/B] The assay is unaffected by icterus (bilirubin < 513 µmol/L or < 30 mg/dL), hemolysis (Hb < 0.372 mmol/L or < 0.600 g/dL), lipemia (Intralipid < 1000 mg/dL) and biotin (< 123 nmol/L or < 30 ng/mL). Criterion:[B] [/B]Recovery within ± 10 % of initial value (concentration range > 1‑15 ng/mL), recovery within ± 15 % of initial value (concentration range > 0.5‑1 ng/mL) and recovery of ± 0.075 ng/mL (concentration range of 0.150‑0.500 ng/mL). Samples should not be taken from patients receiving therapy with high biotin doses (i.e. > 5 mg/day) until at least 8 hours following the last biotin administration. No interference was observed from rheumatoid factors up to a concentration of 1000 IU/mL. In vitro tests were performed on 18 commonly used pharmaceuticals. No interference with the assay was found. Two special drugs were additionally tested. [B][U]Strong interaction with Nandrolone (INN international nonproprietary name, WHO) was found. Do not use samples from patients under Nandrolone treatment[/U]. [/B] In isolated cases, elevated testosterone levels can be seen in samples from female patients with end-stage renal disease (ESRD). Implausible elevated testosterone values in women should be verified by an extraction method or a validated LC‑MS/MS tandem method.5 In rare cases, interference due to extremely high titers of antibodies to analyte‑specific antibodies, streptavidin, or ruthenium can occur. These effects are minimized by a suitable test design. For diagnostic purposes, the results should always be assessed in conjunction with the patient’s medical history, clinical examination, and other findings. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
First blood work after adding Nandrolone
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