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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Finasteride: Suicidality and Psychological Adverse Events in Men Taking Propecia or Proscar
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<blockquote data-quote="madman" data-source="post: 192948" data-attributes="member: 13851"><p><strong>Key Points</strong></p><p><strong></strong></p><p><strong>Question </strong>Is finasteride use associated with more spontaneous reports of suicidality, depression, and/or anxiety?</p><p></p><p><strong>Findings</strong> This pharmacovigilance case-noncase study of 3282 users of finasteride used VigiBase, the World Health Organization’s global database of individual case safety reports, and found a disproportional signal of suicidality, depression, and anxiety associated with finasteride use for alopecia in patients younger than 45 years. No such signal was associated with drugs that had different mechanisms of action but similar indications or with drugs that had similar mechanisms and adverse effect profiles.</p><p></p><p><strong>Meaning</strong> <strong><em><u>This study’s findings suggest that the risk of suicidality, depression, and anxiety should be considered when prescribing finasteride to younger patients with alopecia who may be more vulnerable to the drug’s adverse effects</u>; this association may be biased by stimulated reporting and should be further investigated.</em></strong></p></blockquote><p></p>
[QUOTE="madman, post: 192948, member: 13851"] [B]Key Points Question [/B]Is finasteride use associated with more spontaneous reports of suicidality, depression, and/or anxiety? [B]Findings[/B] This pharmacovigilance case-noncase study of 3282 users of finasteride used VigiBase, the World Health Organization’s global database of individual case safety reports, and found a disproportional signal of suicidality, depression, and anxiety associated with finasteride use for alopecia in patients younger than 45 years. No such signal was associated with drugs that had different mechanisms of action but similar indications or with drugs that had similar mechanisms and adverse effect profiles. [B]Meaning[/B] [B][I][U]This study’s findings suggest that the risk of suicidality, depression, and anxiety should be considered when prescribing finasteride to younger patients with alopecia who may be more vulnerable to the drug’s adverse effects[/U]; this association may be biased by stimulated reporting and should be further investigated.[/I][/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Finasteride: Suicidality and Psychological Adverse Events in Men Taking Propecia or Proscar
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