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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Finasteride (Propecia) Hair Lotion or Foam to Treat Hair Loss in Men and Women
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<blockquote data-quote="madman" data-source="post: 181101" data-attributes="member: 13851"><p><strong>Topical finasteride for the treatment of male androgenetic alopecia and female pattern hair loss:<span style="color: rgb(184, 49, 47)"> a review of the current literature </span></strong></p><p></p><p><span style="color: rgb(0, 0, 0)"><strong>ABSTRACT</strong></span></p><p><span style="color: rgb(0, 0, 0)"><strong></strong></span></p><p><span style="color: rgb(0, 0, 0)"><strong>Background:</strong></span> <span style="color: rgb(0, 0, 0)"><em>Androgenetic alopecia (AGA) is a frequently encountered dermatological concern that impacts a patient’s self-esteem and quality of life. </em></span><em><span style="color: rgb(184, 49, 47)"><em>Finasteride is a selective 5-alpha reductase inhibitor that has been approved for the treatment of male AGA and the off-label use in female pattern hair loss (FPHL); however, its adverse effects may limit its use. </em></span></em><span style="color: rgb(44, 130, 201)"><em><strong><em>Topical finasteride is a new formulation that aims to decrease complications caused by oral administration. </em></strong></em></span></p><p></p><p><strong><span style="color: rgb(0, 0, 0)">Objective:</span> </strong><span style="color: rgb(0, 0, 0)"><em>This review assesses the pharmacology, current therapeutic use, and safety of topical finasteride for the treatment of AGA and FPHL. </em></span></p><p><span style="color: rgb(0, 0, 0)"></span></p><p><span style="color: rgb(0, 0, 0)"><strong>Methods:</strong> <em>A PubMed search was conducted to include all English-language articles on topical finasteride from January 1992 to January 2020. Results: A total of 33 articles including 28 topical finasteride-related articles and 5 AGA-related articles were included in this review. Multiple studies on topical finasteride as the treatment for male AGA and FPHL showed positive results with a favorable safety profile. </em></span></p><p><span style="color: rgb(0, 0, 0)"></span></p><p><span style="color: rgb(0, 0, 0)"><strong>Conclusions:</strong> </span><span style="color: rgb(184, 49, 47)"><em>Topical finasteride is a promising therapeutic option. We emphasize the importance of continued research for the establishment of a novel therapeutic agent.</em></span></p><p></p><p></p><p></p><p></p><p><strong>Conclusion </strong></p><p><strong></strong></p><p><strong><em>This review summarizes the pharmacology, clinical efficacy, and side effects of a topical formulation of finasteride in the treatment of AGA and FPHL. <strong><em><span style="color: rgb(184, 49, 47)">Current data support the therapeutic potential of topical finasteride in increasing hair density and hair diameter while decreasing the systemic adverse effects associated with oral administration.</span></em><span style="color: rgb(44, 130, 201)"> The combination of topical finasteride and minoxidil provides an additional benefit over minoxidil monotherapy and may be a promising treatment option in the future.</span></strong></em></strong><span style="color: rgb(184, 49, 47)"><strong><em><strong> Despite its proven efficacy, the use of topical finasteride is limited due to a smaller number of studies. Further studies are warranted to determine the most efficacious formulations and to investigate the consequences following the long-term use of topical finasteride. </strong></em></strong></span></p></blockquote><p></p>
[QUOTE="madman, post: 181101, member: 13851"] [B]Topical finasteride for the treatment of male androgenetic alopecia and female pattern hair loss:[COLOR=rgb(184, 49, 47)] a review of the current literature [/COLOR][/B] [COLOR=rgb(0, 0, 0)][B]ABSTRACT Background:[/B][/COLOR] [COLOR=rgb(0, 0, 0)][I]Androgenetic alopecia (AGA) is a frequently encountered dermatological concern that impacts a patient’s self-esteem and quality of life. [/I][/COLOR][I][COLOR=rgb(184, 49, 47)][I]Finasteride is a selective 5-alpha reductase inhibitor that has been approved for the treatment of male AGA and the off-label use in female pattern hair loss (FPHL); however, its adverse effects may limit its use. [/I][/COLOR][/I][COLOR=rgb(44, 130, 201)][I][B][I]Topical finasteride is a new formulation that aims to decrease complications caused by oral administration. [/I][/B][/I][/COLOR] [B][COLOR=rgb(0, 0, 0)]Objective:[/COLOR] [/B][COLOR=rgb(0, 0, 0)][I]This review assesses the pharmacology, current therapeutic use, and safety of topical finasteride for the treatment of AGA and FPHL. [/I] [B]Methods:[/B] [I]A PubMed search was conducted to include all English-language articles on topical finasteride from January 1992 to January 2020. Results: A total of 33 articles including 28 topical finasteride-related articles and 5 AGA-related articles were included in this review. Multiple studies on topical finasteride as the treatment for male AGA and FPHL showed positive results with a favorable safety profile. [/I] [B]Conclusions:[/B] [/COLOR][COLOR=rgb(184, 49, 47)][I]Topical finasteride is a promising therapeutic option. We emphasize the importance of continued research for the establishment of a novel therapeutic agent.[/I][/COLOR] [B]Conclusion [I]This review summarizes the pharmacology, clinical efficacy, and side effects of a topical formulation of finasteride in the treatment of AGA and FPHL. [B][I][COLOR=rgb(184, 49, 47)]Current data support the therapeutic potential of topical finasteride in increasing hair density and hair diameter while decreasing the systemic adverse effects associated with oral administration.[/COLOR][/I][COLOR=rgb(44, 130, 201)] The combination of topical finasteride and minoxidil provides an additional benefit over minoxidil monotherapy and may be a promising treatment option in the future.[/COLOR][/B][/I][/B][COLOR=rgb(184, 49, 47)][B][I][B] Despite its proven efficacy, the use of topical finasteride is limited due to a smaller number of studies. Further studies are warranted to determine the most efficacious formulations and to investigate the consequences following the long-term use of topical finasteride. [/B][/I][/B][/COLOR] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Finasteride (Propecia) Hair Lotion or Foam to Treat Hair Loss in Men and Women
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