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ExcelFemale
HRT in Women
Finasteride (Propecia) for Scalp Hair Loss and Excess Facial Hair in Women: Safe and Effective?
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<blockquote data-quote="madman" data-source="post: 223874" data-attributes="member: 13851"><p>Some may experience negative short/long-term sides when using 5α-Reductase inhibitors.</p><p></p><p>No one can say how you will react.</p><p></p><p>You may not have any issues then again you may very well be one of the unlucky ones.</p><p></p><p>We need to tread lightly when trying to manipulate testosterone metabolites estradiol and DHT as they are needed in healthy amounts and are critical to our overall health.</p><p></p><p>Keep in mind that the metabolites estradiol and DHT are needed in healthy amounts to experience the full spectrum of testosterones beneficial effects on mood, energy, libido, erectile function, cardiovascular/brain/bone/tendon/immune system health, body composition, and recovery.</p><p></p><p><em><strong>*Natural testosterone is viewed as the best androgen for substitution in hypogonadal men. The reason behind the selection is that testosterone can be converted to DHT and E2, thus developing the full spectrum of testosterone activities in long-term substitution.</strong></em></p><p></p><p><strong><em>*Considerable evidence exists in the contemporary literature regarding the physiological role of 5a-reductases in the peripheral tissues and CNS and the pathophysiological implication of inhibiting this family of enzymes and blunting biosynthesis of neurosteroids, which are critical biological mediators in the CNS, and contribute to altered mood, cognition, and libido (23–50). Also, significant pre-clinical evidence exists demonstrating that inhibition of 5a-RIs contributes to erectile dysfunction (16–22) and may also contribute to neurological symptoms (Fig. 4 (36).</em></strong></p><p></p><p></p><p></p><p></p><p>You may want to look into topical (solution/foam) Finasteride.</p><p></p><p><strong><em>*In males, the most commonly reported adverse events due to 1 mg/day oral finasteride tablet intake include decreased libido, erectile dysfunction, ejaculation disorder, and impotence.4 <u>For females, the reported adverse effects are sexual dysfunction, menstrual irregularity, headache, and hypertrichosis</u>.4 <u>Most adverse events are potentially linked with DHT reduction in serum and other sexual organs' tissues</u>.27 <u>In such cases, the topical formulation may be an alternative to oral finasteride to minimize systemic adverse events</u></em></strong></p><p></p><p></p><p></p><p></p><p>Here are some of my earlier threads:</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/sexual-problems-in-men-with-alopecia-treated-with-oral-finasteride-are-topical-solutions-better.16571/[/URL]</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/efficacy-of-topical-combination-of-0-25-finasteride-and-3-minoxidil-versus-3-minoxidil-solution-in-female-pattern-hair-loss.16579/[/URL]</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/finasteride-propecia-hair-lotion-or-foam-to-treat-hair-loss-in-men-and-women.21273/[/URL]</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/topical-finasteride-for-male-androgenetic-alopecia.24239/[/URL]</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/guideline-for-the-treatment-of-alopecia-in-women-and-men.22386/[/URL]</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/practical-approach-to-hyperandrogenism-in-women.24293/[/URL]</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/treatment-options-for-androgenetic-alopecia.24369/[/URL]</p></blockquote><p></p>
[QUOTE="madman, post: 223874, member: 13851"] Some may experience negative short/long-term sides when using 5α-Reductase inhibitors. No one can say how you will react. You may not have any issues then again you may very well be one of the unlucky ones. We need to tread lightly when trying to manipulate testosterone metabolites estradiol and DHT as they are needed in healthy amounts and are critical to our overall health. Keep in mind that the metabolites estradiol and DHT are needed in healthy amounts to experience the full spectrum of testosterones beneficial effects on mood, energy, libido, erectile function, cardiovascular/brain/bone/tendon/immune system health, body composition, and recovery. [I][B]*Natural testosterone is viewed as the best androgen for substitution in hypogonadal men. The reason behind the selection is that testosterone can be converted to DHT and E2, thus developing the full spectrum of testosterone activities in long-term substitution.[/B][/I] [B][I]*Considerable evidence exists in the contemporary literature regarding the physiological role of 5a-reductases in the peripheral tissues and CNS and the pathophysiological implication of inhibiting this family of enzymes and blunting biosynthesis of neurosteroids, which are critical biological mediators in the CNS, and contribute to altered mood, cognition, and libido (23–50). Also, significant pre-clinical evidence exists demonstrating that inhibition of 5a-RIs contributes to erectile dysfunction (16–22) and may also contribute to neurological symptoms (Fig. 4 (36).[/I][/B] You may want to look into topical (solution/foam) Finasteride. [B][I]*In males, the most commonly reported adverse events due to 1 mg/day oral finasteride tablet intake include decreased libido, erectile dysfunction, ejaculation disorder, and impotence.4 [U]For females, the reported adverse effects are sexual dysfunction, menstrual irregularity, headache, and hypertrichosis[/U].4 [U]Most adverse events are potentially linked with DHT reduction in serum and other sexual organs' tissues[/U].27 [U]In such cases, the topical formulation may be an alternative to oral finasteride to minimize systemic adverse events[/U][/I][/B] Here are some of my earlier threads: [URL unfurl="true"]https://www.excelmale.com/forum/threads/sexual-problems-in-men-with-alopecia-treated-with-oral-finasteride-are-topical-solutions-better.16571/[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/efficacy-of-topical-combination-of-0-25-finasteride-and-3-minoxidil-versus-3-minoxidil-solution-in-female-pattern-hair-loss.16579/[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/finasteride-propecia-hair-lotion-or-foam-to-treat-hair-loss-in-men-and-women.21273/[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/topical-finasteride-for-male-androgenetic-alopecia.24239/[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/guideline-for-the-treatment-of-alopecia-in-women-and-men.22386/[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/practical-approach-to-hyperandrogenism-in-women.24293/[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/treatment-options-for-androgenetic-alopecia.24369/[/URL] [/QUOTE]
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ExcelFemale
HRT in Women
Finasteride (Propecia) for Scalp Hair Loss and Excess Facial Hair in Women: Safe and Effective?
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