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<blockquote data-quote="Systemlord" data-source="post: 111419" data-attributes="member: 15832"><p>I originally started out TRT injecting once weekly, as time went on I began to feel really bad after 3-4 days. My SHBG is fluctuates between 16-18 and unless I'm injecting 16-20mg EOD I feel mediocre. I respond poorly to TRT injecting twice weekly even with good numbers. You need to test SHBG and monitor your estrogen level using the E2 sensitive LC/MS/MS labs.</p><p></p><p>I suspect your SHBG is lower, 75mg once weekly got me to 440 on trough day (right before injection). You have a higher dosage and are scoring lower, if low SHBG is confirmed you just may need to inject everyday or EOD. You can inject using Easy Tough 27-29 gauge insulin syringes in shoulder or outer quads SQ or IM, SQ is great for lower SHBG guys.</p><p></p><p>I would also like to see thyroid labs, and not just TSH, but Free T3, Free T4, Reverse T3 and antibodies. Low testosterone and low thyroid share common symptoms.</p></blockquote><p></p>
[QUOTE="Systemlord, post: 111419, member: 15832"] I originally started out TRT injecting once weekly, as time went on I began to feel really bad after 3-4 days. My SHBG is fluctuates between 16-18 and unless I'm injecting 16-20mg EOD I feel mediocre. I respond poorly to TRT injecting twice weekly even with good numbers. You need to test SHBG and monitor your estrogen level using the E2 sensitive LC/MS/MS labs. I suspect your SHBG is lower, 75mg once weekly got me to 440 on trough day (right before injection). You have a higher dosage and are scoring lower, if low SHBG is confirmed you just may need to inject everyday or EOD. You can inject using Easy Tough 27-29 gauge insulin syringes in shoulder or outer quads SQ or IM, SQ is great for lower SHBG guys. I would also like to see thyroid labs, and not just TSH, but Free T3, Free T4, Reverse T3 and antibodies. Low testosterone and low thyroid share common symptoms. [/QUOTE]
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