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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Finally got great testosterone levels- but have questions about cortisol, thyroid, IgF, DHEA-S
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<blockquote data-quote="Vettester Chris" data-source="post: 23347" data-attributes="member: 696"><p>SomeG, going off of what I see, I actually do suspect thyroid issues. Like Nelson stated already, we do need the free serum on both T4 &amp; T3, plus you will want Reverse T3, and anitbodies (TPO &amp; TgAb).</p><p></p><p>Here's my reasoning&nbsp; ... Going on your Total T4 &amp; T3, take notice with how far apart each lab is from the other within the respective reference range. Total T4 is at 30.6% of the ref range value, Total T3 is at 76.9% of ref. range value. Normal function would usually have both of these semi-close to each other. I suspect free serum levels will follow similar suit, but would want to know for sure. </p><p></p><p>Additionally, I suspect possible pooling with T3, meaning T3 isn't getting into the cells, it's just building up. The lab that will counter-check this will be Reverse T3 and the comparative ratio to FT3.</p><p></p><p>This is one KEY example of why TSH is misleading ... If FT3 is pooling, then the feedback loop is indicating that thyroid hormone levels are up, which in turn directs the pituitary to reduce the demand for further hormone production, which in itself reduces TSH levels. </p><p></p><p>This can be common with Hashis and other thyroid disorders, and evident when transport agents like cortisol, iron, ferritin, and in some cases electrolytes &amp; D3 play a role with T3 productivity. With "transport agents", I am referring to specific hormones/elements/proteins that play a vital role with T3 getting into the body. Cortisol &amp; Iron/Ferritin are usually the two key components that factor into this.</p><p></p><p>Your cortisol serum lab basically doesn't elaborate anything. There is so much variance between AM &amp; PM, and the only effective way to really gauge it is with a 24 hour -4x saliva kit, which is the gold standard. The cortisol kit should also include a DHEA saliva lab for the sake of getting the adrenal overview with a DHEA/cortisol correlation analysis. The iron &amp; ferritin should remain drawn with blood serum, and I would also include at least a TIBC with it. </p><p></p><p>My gut says your physician(s) won't buy into much of this, due to the fact that they are running these useless "index" labs. Those labs tell them virtually NOTHING!<u> And do me a favor,</u> double check that T3 lab. <u><strong>You say "T3 was 32" .. Please confirm that this didn't say T3 Uptake?? </strong></u>If it did, then everything I've been saying at the top with the reference range comparisons was just an exercise. If it it is a T3, meaning "Total T3", then the reference range discussions stands, I would evaluate further ... I throw this out because when doctors start ordering some of these useless "index" thyroid labs, they usually throw that Uptake in as well. Sounds snazzy and important, but it's worthless!</p></blockquote><p></p>
[QUOTE="Vettester Chris, post: 23347, member: 696"] SomeG, going off of what I see, I actually do suspect thyroid issues. Like Nelson stated already, we do need the free serum on both T4 & T3, plus you will want Reverse T3, and anitbodies (TPO & TgAb). Here's my reasoning ... Going on your Total T4 & T3, take notice with how far apart each lab is from the other within the respective reference range. Total T4 is at 30.6% of the ref range value, Total T3 is at 76.9% of ref. range value. Normal function would usually have both of these semi-close to each other. I suspect free serum levels will follow similar suit, but would want to know for sure. Additionally, I suspect possible pooling with T3, meaning T3 isn't getting into the cells, it's just building up. The lab that will counter-check this will be Reverse T3 and the comparative ratio to FT3. This is one KEY example of why TSH is misleading ... If FT3 is pooling, then the feedback loop is indicating that thyroid hormone levels are up, which in turn directs the pituitary to reduce the demand for further hormone production, which in itself reduces TSH levels. This can be common with Hashis and other thyroid disorders, and evident when transport agents like cortisol, iron, ferritin, and in some cases electrolytes & D3 play a role with T3 productivity. With "transport agents", I am referring to specific hormones/elements/proteins that play a vital role with T3 getting into the body. Cortisol & Iron/Ferritin are usually the two key components that factor into this. Your cortisol serum lab basically doesn't elaborate anything. There is so much variance between AM & PM, and the only effective way to really gauge it is with a 24 hour -4x saliva kit, which is the gold standard. The cortisol kit should also include a DHEA saliva lab for the sake of getting the adrenal overview with a DHEA/cortisol correlation analysis. The iron & ferritin should remain drawn with blood serum, and I would also include at least a TIBC with it. My gut says your physician(s) won't buy into much of this, due to the fact that they are running these useless "index" labs. Those labs tell them virtually NOTHING![U] And do me a favor,[/U] double check that T3 lab. [U][B]You say "T3 was 32" .. Please confirm that this didn't say T3 Uptake?? [/B][/U]If it did, then everything I've been saying at the top with the reference range comparisons was just an exercise. If it it is a T3, meaning "Total T3", then the reference range discussions stands, I would evaluate further ... I throw this out because when doctors start ordering some of these useless "index" thyroid labs, they usually throw that Uptake in as well. Sounds snazzy and important, but it's worthless! [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Finally got great testosterone levels- but have questions about cortisol, thyroid, IgF, DHEA-S
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