Sure. For some men, Clomid is just awful. For others, it works very well.
The only way to find out to which group you belong is to try. And "try" means initiating therapy, waiting about 3 weeks, running labs, evaluating them, then making any necessary adjustments. That is because how you feel, AND how well it is working, may be worlds apart.
Too many men just quit after a few days. They did not give things time to work. Having said that, vision changes is an automatic No Go for clomiphene therapy. We just don't mess around with our eyes.
You have to watch LH and FSH--to see if it is working. That also decides your dose.
Watch Total Testosterone level. IF LH is up, and T is not, are you suffering primary failure? And remember, LH production is very cyclical.
You have to watch SHBG. IF it rises, you will need to produce more testosterone to overcome it.
IF it just blocks estrogen--subjectively--you are usually all good. But some men get estrogenic symptoms with it. The chance of that happening is lessened by starting at a lower dose, such as 12.5mgs per day.
"Start low/Go slow" never found a more poignant example. That way you know which direction to go when titrating dose.
The bottom line is you need someone who really knows what they are doing to direct your care. But living well on just a single tab per day certainly has its benefits.
