Fee Estriol vs. Free Estradiol test

In line with observations by Vince Carter that in low SHBG guys there tends to be more Free T and therefore more Free E2, and that maybe because of that we should be checking the free Estradiol more than the normal E2 (and that maybe because of that also, an E2 level around 20 might be better for us, due to higher free E2): I have a lot of free T (in the 30s) with Total T < 1k, so I am wondering what my free Estradiol looks like. However, I have a problem:

I don't have access to a free estradiol test
I do however have access to a free estriol test

Does anybody know if this will be close enough or useful to determine what my free estrogen looks like even though it won't be "free estradiol"? Does anybody know if the free estriol test is useful for men on TRT in general?

Background: My plan is to check this once I get E2 under control and the main figure is in range (i.e. in the 30s), slowly getting there.
 
In line with observations by Vince Carter that in low SHBG guys there tends to be more Free T and therefore more Free E2, and that maybe because of that we should be checking the free Estradiol more than the normal E2 (and that maybe because of that also, an E2 level around 20 might be better for us, due to higher free E2): I have a lot of free T (in the 30s) with Total T < 1k, so I am wondering what my free Estradiol looks like. However, I have a problem:

I don't have access to a free estradiol test
I do however have access to a free estriol test

Does anybody know if this will be close enough or useful to determine what my free estrogen looks like even though it won't be "free estradiol"? Does anybody know if the free estriol test is useful for men on TRT in general?

Background: My plan is to check this once I get E2 under control and the main figure is in range (i.e. in the 30s), slowly getting there.
It provides you and your doctor with no useful information. Estradiol and estriol are two different hormones. It is almost undetectible in when who aren't pregnant. As for men...well, it's a moot point.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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