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ExcelFemale
HRT in Women
FDA Panel Backs Fibanserin, the First Female Libido Drug
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<blockquote data-quote="Nelson Vergel" data-source="post: 19809" data-attributes="member: 3"><p><strong><a href="http://www.forbes.com/sites/davidkroll/2015/06/14/the-true-significance-of-flibanserins-modest-boost-to-female-sexual-desire/" target="_blank">The True Significance Of Flibanserin's 'Modest' Boost To Female Sexual Desire</a></strong></p><p></p><p>"Most public discussion has focused on the conclusion that flibanserin increases a woman's sexually satisfying experiences by one per month over placebo. In part, that's the easiest way to summarize the 306-page briefing document Sprout released for last week's FDA hearing, and I even used it in my articles.Whitehead says that representation obscures the context in which those increases occurred. In the most recent of three pivotal randomized, double-blind, placebo-controlled trials, women taking flibanserin in a single nighttime dose went from an average of 2.5 sexually satisfying events per month to 5.0 per month. In contrast, women in the placebo group went from 2.7 at baseline to 3.5.</p><p></p><p>So what the data show is an increase of 2.5 events per month, of which only 0.8 could be credited to placebo.</p><p></p><p></p><p>Consider if we reported instead that women doubled their number of satisfying sexual experiences (from 2.5 to 5.0) and their increase was triple that seen with placebo (increase of 0.8 vs. 2.5). That would also be true. And perhaps the perception of efficacy might be far more positive."</p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 19809, member: 3"] [b][URL="http://www.forbes.com/sites/davidkroll/2015/06/14/the-true-significance-of-flibanserins-modest-boost-to-female-sexual-desire/"]The True Significance Of Flibanserin's 'Modest' Boost To Female Sexual Desire[/URL][/b] "Most public discussion has focused on the conclusion that flibanserin increases a woman's sexually satisfying experiences by one per month over placebo. In part, that's the easiest way to summarize the 306-page briefing document Sprout released for last week's FDA hearing, and I even used it in my articles.Whitehead says that representation obscures the context in which those increases occurred. In the most recent of three pivotal randomized, double-blind, placebo-controlled trials, women taking flibanserin in a single nighttime dose went from an average of 2.5 sexually satisfying events per month to 5.0 per month. In contrast, women in the placebo group went from 2.7 at baseline to 3.5. So what the data show is an increase of 2.5 events per month, of which only 0.8 could be credited to placebo. Consider if we reported instead that women doubled their number of satisfying sexual experiences (from 2.5 to 5.0) and their increase was triple that seen with placebo (increase of 0.8 vs. 2.5). That would also be true. And perhaps the perception of efficacy might be far more positive." [/QUOTE]
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ExcelFemale
HRT in Women
FDA Panel Backs Fibanserin, the First Female Libido Drug
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