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FAT LOSS DIFFICULTY
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<blockquote data-quote="mcs" data-source="post: 219512" data-attributes="member: 12"><p>Thanks for your input.</p><p></p><p>I have been familiar with Volek/Phinney's work for some time and am more than aware of the effects of gluconeogenesis. While I think that the science has merit, and perhaps I'm wrong, but I don't think that strict keto is sustainable for long periods of time and definitely not a way to go if you are trying to maintain/build lean mass or prevent sarcopenia as we age. Adequate protein intake to the tune of 1g/pound of body weight is still a good rule of thumb. Yes, perhaps CKD with carb refeeds is the key. Saturated fats are also something to watch for if you have the ACE and FTO genetic polymorphisms in which keto diets can actually be detrimental. I wonder what affect restricting my carbs has had on suppressing testosterone and T3 levels as well. The keto pundits will defend it by saying that reduced T3 is an adaptive response and non-pathogenic but I disagree. I think the hibernation factor comes into account on long-term keto that can suppress thyroid function and, as well, testosterone production. If I finally take the plunge and go on TRT, then protein synthesis will be increased and my protein intake will have to go even higher.</p><p></p><p>I have been through bevies of endocrinologists and other physicians through the years, none of which got my thyroid optimized to this day. I have had now 12 years experience of experimenting with every conceivable thyroid medication and combination and still can't achieve a suppressed enough TSH, the extensive subject of my other threads.</p></blockquote><p></p>
[QUOTE="mcs, post: 219512, member: 12"] Thanks for your input. I have been familiar with Volek/Phinney's work for some time and am more than aware of the effects of gluconeogenesis. While I think that the science has merit, and perhaps I'm wrong, but I don't think that strict keto is sustainable for long periods of time and definitely not a way to go if you are trying to maintain/build lean mass or prevent sarcopenia as we age. Adequate protein intake to the tune of 1g/pound of body weight is still a good rule of thumb. Yes, perhaps CKD with carb refeeds is the key. Saturated fats are also something to watch for if you have the ACE and FTO genetic polymorphisms in which keto diets can actually be detrimental. I wonder what affect restricting my carbs has had on suppressing testosterone and T3 levels as well. The keto pundits will defend it by saying that reduced T3 is an adaptive response and non-pathogenic but I disagree. I think the hibernation factor comes into account on long-term keto that can suppress thyroid function and, as well, testosterone production. If I finally take the plunge and go on TRT, then protein synthesis will be increased and my protein intake will have to go even higher. I have been through bevies of endocrinologists and other physicians through the years, none of which got my thyroid optimized to this day. I have had now 12 years experience of experimenting with every conceivable thyroid medication and combination and still can't achieve a suppressed enough TSH, the extensive subject of my other threads. [/QUOTE]
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