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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Fast Metabolizers?
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<blockquote data-quote="Cataceous" data-source="post: 197505" data-attributes="member: 38109"><p>No denying there are a few people reporting response-to-dose much lower than normal. Even in the past day:</p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/high-dose-low-total.23018/[/URL]</p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/switched-to-ed-protocol-with-same-dose-and-ft-dropped.23019/#post-197502[/URL]</p><p>Contributing factors may sometimes include low SHBG and high body weight. Presumably they also have high-end metabolic clearance rates for testosterone. Only detailed measurements under controlled conditions would adequately explain the reported observations.</p><p></p><p>The bottom line though is that 3-9 mg is the reported range for daily testosterone production in men, and this probably represents at least two standard deviations about the mean. In other words, exogenous testosterone dosed in this range will produce normal serum levels in the vast majority of healthy men. Translated to TRT, those who need more than about 120 mg T cypionate per week to reach at least low-normal average serum T are uncommon in the population at large.</p><p></p><p>This is similar to my own response and is not particularly extreme. Basically, 4 mg of testosterone daily is sufficient to maintain normal serum levels. It presumably does reflect a below-average MCR(T).</p></blockquote><p></p>
[QUOTE="Cataceous, post: 197505, member: 38109"] No denying there are a few people reporting response-to-dose much lower than normal. Even in the past day: [URL unfurl="true"]https://www.excelmale.com/forum/threads/high-dose-low-total.23018/[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/switched-to-ed-protocol-with-same-dose-and-ft-dropped.23019/#post-197502[/URL] Contributing factors may sometimes include low SHBG and high body weight. Presumably they also have high-end metabolic clearance rates for testosterone. Only detailed measurements under controlled conditions would adequately explain the reported observations. The bottom line though is that 3-9 mg is the reported range for daily testosterone production in men, and this probably represents at least two standard deviations about the mean. In other words, exogenous testosterone dosed in this range will produce normal serum levels in the vast majority of healthy men. Translated to TRT, those who need more than about 120 mg T cypionate per week to reach at least low-normal average serum T are uncommon in the population at large. This is similar to my own response and is not particularly extreme. Basically, 4 mg of testosterone daily is sufficient to maintain normal serum levels. It presumably does reflect a below-average MCR(T). [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Fast Metabolizers?
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