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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
fanconi syndrome and trt
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<blockquote data-quote="Nelson Vergel" data-source="post: 8547" data-attributes="member: 3"><p>Tmckensie</p><p></p><p>I am so sorry to hear. You actually got a diagnosis?</p><p></p><p>I did a google scholar search and found nothing about testosterone replacement in patients with Fanconi syndrome.</p><p></p><p>I found this good reference:</p><p></p><p>The treatment of a child with Fanconi syndrome mainly consists of the replacement of substances lost in the urine. Prominent among these substances are fluids and electrolytes.</p><p>Dehydration due to polyuria must be prevented by allowing free access to water; treat dehydration with either oral or parenteral solutions.</p><p></p><p>Metabolic acidosis due to the loss of bicarbonate is corrected by the administration of alkali, usually 3-10 mg/kg/d of sodium bicarbonate in divided doses.</p><p></p><p>Addition of a diuretic, such as 1-3 mg/kg/d of hydrochlorothiazide, may be necessary to avoid volume expansion, which magnifies the excretion of bicarbonate by lowering the renal threshold. Unfortunately, the diuretic increases potassium wasting and thus the need to augment potassium supplementation in the form of potassium bicarbonate, citrate, or acetate.</p><p></p><p>Correction of metabolic acidosis is beneficial but is not sufficient for the treatment of bone disease. Phosphate and vitamin D supplementation are also necessary.</p><p></p><p>Normalization of serum phosphate levels may be achieved by administering 1-3 g/d of supplemental phosphate. Administration should start at the lower level and be slowly increased over several weeks to minimize GI symptoms.</p><p>Vitamin D, administered as 1,25-dihydroxyvitamin D3 or 1a-hydroxyvitamin D3, is preferred because liver and/or renal hydroxylation may be impaired in patients with Fanconi syndrome.</p><p>The losses of glucose, amino acids, and uric acid are not usually symptomatic and do not require replacement. Recently, carnitine supplementation has been tried in an attempt to increase muscle strength; however, results have been mixed.</p><p><a href="http://emedicine.medscape.com/article/981774-treatment" target="_blank">http://emedicine.medscape.com/article/981774-treatment</a></p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 8547, member: 3"] Tmckensie I am so sorry to hear. You actually got a diagnosis? I did a google scholar search and found nothing about testosterone replacement in patients with Fanconi syndrome. I found this good reference: The treatment of a child with Fanconi syndrome mainly consists of the replacement of substances lost in the urine. Prominent among these substances are fluids and electrolytes. Dehydration due to polyuria must be prevented by allowing free access to water; treat dehydration with either oral or parenteral solutions. Metabolic acidosis due to the loss of bicarbonate is corrected by the administration of alkali, usually 3-10 mg/kg/d of sodium bicarbonate in divided doses. Addition of a diuretic, such as 1-3 mg/kg/d of hydrochlorothiazide, may be necessary to avoid volume expansion, which magnifies the excretion of bicarbonate by lowering the renal threshold. Unfortunately, the diuretic increases potassium wasting and thus the need to augment potassium supplementation in the form of potassium bicarbonate, citrate, or acetate. Correction of metabolic acidosis is beneficial but is not sufficient for the treatment of bone disease. Phosphate and vitamin D supplementation are also necessary. Normalization of serum phosphate levels may be achieved by administering 1-3 g/d of supplemental phosphate. Administration should start at the lower level and be slowly increased over several weeks to minimize GI symptoms. Vitamin D, administered as 1,25-dihydroxyvitamin D3 or 1a-hydroxyvitamin D3, is preferred because liver and/or renal hydroxylation may be impaired in patients with Fanconi syndrome. The losses of glucose, amino acids, and uric acid are not usually symptomatic and do not require replacement. Recently, carnitine supplementation has been tried in an attempt to increase muscle strength; however, results have been mixed. [url]http://emedicine.medscape.com/article/981774-treatment[/url] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
fanconi syndrome and trt
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