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KEY POINTS

*Botulinum toxin functions by paralyzing or weakening muscles of facial expression and thereby diminishing the appearance of mimetic lines

*Hyaluronic acid fillers have a wide variety of clinical applications in facial aesthetic medicine, and variation in filler density determines indication for location and depth of injection

*Chemical peels predictably rejuvenate the face and vary in depth of penetration from superficial to deep; chemoexfoliation coagulates proteins in the skin and induces regeneration of collagen and keratinocytes

*Topical aesthetic medicines are gaining popularity for the treatment of acne, photodamage, fine rhytids, and dyschromia

*Patients with significant horizontal forehead rhytids often have a standing static elevation of the brow by activation of the frontalis— be judicious with neurotoxin injection to avoid brow ptosis

*Inadequate weakening of the lateral frontalis can result in lateral brow “peaking” and can be corrected with a small amount of neurotoxin in the lateral frontalis

*The depth of penetration of a chemical peel depends on the mechanism of chemoexfoliation

*Nonself-neutralizing peels such as GA will continue to keratocoagulate for the duration of their contact with the skin and can reach deeper layers by prolonged skin contact

*Self-neutralizing chemical peels, such as salicylic acid, reach an endpoint after which they no longer penetrate the dermis

*Patients should wait for 6 to 12 months after stopping isotretinoin (Accutane) before undergoing surgical or nonsurgical cosmetic procedures such as laser resurfacing or chemical peels

<blockquote data-quote="madman" data-source="post: 216451" data-attributes="member: 13851">KEY POINTS *Botulinum toxin functions by paralyzing or weakening muscles of facial expression and thereby diminishing the appearance of mimetic lines *Hyaluronic acid fillers have a wide variety of clinical applications in facial aesthetic medicine, and variation in filler density determines indication for location and depth of injection *Chemical peels predictably rejuvenate the face and vary in depth of penetration from superficial to deep; chemoexfoliation coagulates proteins in the skin and induces regeneration of collagen and keratinocytes *Topical aesthetic medicines are gaining popularity for the treatment of acne, photodamage, fine rhytids, and dyschromia*Patients with significant horizontal forehead rhytids often have a standing static elevation of the brow by activation of the frontalis— be judicious with neurotoxin injection to avoid brow ptosis *Inadequate weakening of the lateral frontalis can result in lateral brow “peaking” and can be corrected with a small amount of neurotoxin in the lateral frontalis *The depth of penetration of a chemical peel depends on the mechanism of chemoexfoliation *Nonself-neutralizing peels such as GA will continue to keratocoagulate for the duration of their contact with the skin and can reach deeper layers by prolonged skin contact *Self-neutralizing chemical peels, such as salicylic acid, reach an endpoint after which they no longer penetrate the dermis *Patients should wait for 6 to 12 months after stopping isotretinoin (Accutane) before undergoing surgical or nonsurgical cosmetic procedures such as laser resurfacing or chemical peels</blockquote>

[QUOTE="madman, post: 216451, member: 13851"] [B]KEY POINTS [/B] [I][B]*Botulinum toxin functions by paralyzing or weakening muscles of facial expression and thereby diminishing the appearance of mimetic lines *Hyaluronic acid fillers have a wide variety of clinical applications in facial aesthetic medicine, and variation in filler density determines indication for location and depth of injection *Chemical peels predictably rejuvenate the face and vary in depth of penetration from superficial to deep; chemoexfoliation coagulates proteins in the skin and induces regeneration of collagen and keratinocytes [/B][/I] [B][I]*Topical aesthetic medicines are gaining popularity for the treatment of acne, photodamage, fine rhytids, and dyschromia[/I][/B] [I][B]*Patients with significant horizontal forehead rhytids often have a standing static elevation of the brow by activation of the frontalis— be judicious with neurotoxin injection to avoid brow ptosis *Inadequate weakening of the lateral frontalis can result in lateral brow “peaking” and can be corrected with a small amount of neurotoxin in the lateral frontalis *The depth of penetration of a chemical peel depends on the mechanism of chemoexfoliation *Nonself-neutralizing peels such as GA will continue to keratocoagulate for the duration of their contact with the skin and can reach deeper layers by prolonged skin contact *Self-neutralizing chemical peels, such as salicylic acid, reach an endpoint after which they no longer penetrate the dermis [/B][/I] [B][I]*Patients should wait for 6 to 12 months after stopping isotretinoin (Accutane) before undergoing surgical or nonsurgical cosmetic procedures such as laser resurfacing or chemical peels[/I][/B] [/QUOTE]

Verification

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038