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Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
EXTENDED-RELEASE FORMULATIONS OF HUMAN CHORIONIC GONADOTROPIN (HCG)
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<blockquote data-quote="madman" data-source="post: 238299" data-attributes="member: 13851"><p>It gets even better!</p><p></p><p>Again you heard it here first only at Nelson's Excelmale!</p><p></p><p></p><p>[URL unfurl="true"]https://www.europaomdehoek.nl/projecten/androsphere[/URL]</p><p></p><h3>Androsphere<strong>™</strong></h3><p><strong>Duration:</strong> <em>from December 1, 2021, to August 31, 2023</em></p><p></p><p><strong>Grant Recipient:</strong><em> InnoCore Technologies BV</em></p><p><em></em></p><p><em></em></p><p><em></em></p><p><em><strong>In this valorization project, the Groningen consortium, which consists of InnoCore Pharmaceuticals and PolyVation, <u>will further develop and evaluate an innovative new drug, AndroSphere™, in a 'First-in-Man' phase 1 clinical trial</u>.</strong> <strong><u>AndroSphere™ is a long-acting injectable drug designed specifically for the treatment of hypogonadotropic hypogonadism (HH)</u>, a condition that leads to insufficient testosterone production in men. Low testosterone causes symptoms that limit their daily lives, such as severe fatigue, depression, anemia, and sexual dysfunction.</strong></em></p><p><em><strong></strong></em></p><p><em><strong>For men with HH, only testosterone-based therapies are currently used.<u> An important side effect of testosterone treatment is the suppression of the body's own testosterone</u>. <u>This means, among other things, that the fertility of men undergoing testosterone therapy decreases sharply and the testicles become smaller (testicular atrophy)</u>. Because of this side effect, many men with HH go untreated. <u>Treatment with human chorionic gonadotropin (hCG) does not have this side effect and has even been approved for the treatment of HH</u>. Unfortunately, hCG in its current dosage form has not proven suitable for long-term treatments, because it has to be administered by injection several times a week and is therefore experienced as too burdensome and unpleasant by the patient.</strong> </em></p><p></p><p><strong><em>Using InnoCore's <u>long-acting injectable microsphere technology based on biodegradable SynBiosys polymers, which will be produced by PolyVation, AndroSphere™ is able to release hCG in a sustained and controlled manner, requiring only a single injection per month</u>. <u>In addition, the encapsulation of the protein in the biodegradable polymeric microspheres increases the stability of hCG, making the therapy suitable for home use and self-administration reducing the need for a single injection per month</u>. </em></strong></p><p></p><p><em><strong>The AndroSphere™ project distinguishes itself by contributing to the training and development of (new) employees, and the maintenance and creation of new employment in the Northern Netherlands in the short and (medium) long term. <u>In addition, AndroSphere™ will have a positive impact on the health of people with HH, contributing to increased physical activity, improvement in mood and fewer depressive symptoms, and continued participation in the labor process</u>. All this contributes to an improvement in inclusiveness and thus economic and social sustainability.</strong></em></p></blockquote><p></p>
[QUOTE="madman, post: 238299, member: 13851"] It gets even better! Again you heard it here first only at Nelson's Excelmale! [URL unfurl="true"]https://www.europaomdehoek.nl/projecten/androsphere[/URL] [HEADING=2]Androsphere[B]™[/B][/HEADING] [B]Duration:[/B] [I]from December 1, 2021, to August 31, 2023[/I] [B]Grant Recipient:[/B][I] InnoCore Technologies BV [B]In this valorization project, the Groningen consortium, which consists of InnoCore Pharmaceuticals and PolyVation, [U]will further develop and evaluate an innovative new drug, AndroSphere™, in a 'First-in-Man' phase 1 clinical trial[/U].[/B] [B][U]AndroSphere™ is a long-acting injectable drug designed specifically for the treatment of hypogonadotropic hypogonadism (HH)[/U], a condition that leads to insufficient testosterone production in men. Low testosterone causes symptoms that limit their daily lives, such as severe fatigue, depression, anemia, and sexual dysfunction. For men with HH, only testosterone-based therapies are currently used.[U] An important side effect of testosterone treatment is the suppression of the body's own testosterone[/U]. [U]This means, among other things, that the fertility of men undergoing testosterone therapy decreases sharply and the testicles become smaller (testicular atrophy)[/U]. Because of this side effect, many men with HH go untreated. [U]Treatment with human chorionic gonadotropin (hCG) does not have this side effect and has even been approved for the treatment of HH[/U]. Unfortunately, hCG in its current dosage form has not proven suitable for long-term treatments, because it has to be administered by injection several times a week and is therefore experienced as too burdensome and unpleasant by the patient.[/B] [/I] [B][I]Using InnoCore's [U]long-acting injectable microsphere technology based on biodegradable SynBiosys polymers, which will be produced by PolyVation, AndroSphere™ is able to release hCG in a sustained and controlled manner, requiring only a single injection per month[/U]. [U]In addition, the encapsulation of the protein in the biodegradable polymeric microspheres increases the stability of hCG, making the therapy suitable for home use and self-administration reducing the need for a single injection per month[/U]. [/I][/B] [I][B]The AndroSphere™ project distinguishes itself by contributing to the training and development of (new) employees, and the maintenance and creation of new employment in the Northern Netherlands in the short and (medium) long term. [U]In addition, AndroSphere™ will have a positive impact on the health of people with HH, contributing to increased physical activity, improvement in mood and fewer depressive symptoms, and continued participation in the labor process[/U]. All this contributes to an improvement in inclusiveness and thus economic and social sustainability.[/B][/I] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
EXTENDED-RELEASE FORMULATIONS OF HUMAN CHORIONIC GONADOTROPIN (HCG)
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