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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Exercise Improves Hip Bone but Not Lumbar Bone Density in Chemically Castrated Men
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<blockquote data-quote="Nelson Vergel" data-source="post: 2597" data-attributes="member: 3"><p>Many men with prostate cancer receive androgen suppression therapy to decrease their testosterone to castrate levels. Those men what a lot of quality of life issues and body changes. They loss sex drive, have ED, loss bone density and lean mass, and gain fat. It is a very difficult patient population after cancer is treated since most doctors fear that giving them testosterone will fuel any potentially hidden cancer cells. This study shows that exercise may at least improve some of the bone mass lost in those men.<a href="http://www.ncbi.nlm.nih.gov/pubmed/24170604#" target="_blank"></a></p><p><a href="http://www.ncbi.nlm.nih.gov/pubmed/24170604#" target="_blank"></a></p><p><a href="http://www.ncbi.nlm.nih.gov/pubmed/24170604#" target="_blank"></a></p><p><a href="http://www.ncbi.nlm.nih.gov/pubmed/24170604#" target="_blank"></a></p><p><a href="http://www.ncbi.nlm.nih.gov/pubmed/24170604#" target="_blank"></a></p><p><a href="http://www.ncbi.nlm.nih.gov/pubmed/24170604#" target="_blank"></a></p><p><a href="http://www.ncbi.nlm.nih.gov/pubmed/24170604#" target="_blank"></a></p><p><a href="http://www.ncbi.nlm.nih.gov/pubmed/24170604#" target="_blank">J Am Assoc Nurse Pract.</a> 2013 Aug 27. doi: 10.1002/2327-6924.12066. [Epub ahead of print]</p><p><strong>Self-reported exercise and bone mineral density in prostate cancer patients receiving androgen deprivation therapy.</strong><a href="http://www.ncbi.nlm.nih.gov/pubmed?term=Mennen-Winchell%20LJ%5BAuthor%5D&cauthor=true&cauthor_uid=24170604" target="_blank">Mennen-Winchell LJ</a>, <a href="http://www.ncbi.nlm.nih.gov/pubmed?term=Grigoriev%20V%5BAuthor%5D&cauthor=true&cauthor_uid=24170604" target="_blank">Grigoriev V</a>, <a href="http://www.ncbi.nlm.nih.gov/pubmed?term=Alpert%20P%5BAuthor%5D&cauthor=true&cauthor_uid=24170604" target="_blank">Alpert P</a>, <a href="http://www.ncbi.nlm.nih.gov/pubmed?term=Dos%20Santos%20H%5BAuthor%5D&cauthor=true&cauthor_uid=24170604" target="_blank">Dos Santos H</a>, <a href="http://www.ncbi.nlm.nih.gov/pubmed?term=Tonstad%20S%5BAuthor%5D&cauthor=true&cauthor_uid=24170604" target="_blank">Tonstad S</a>.</p><p>[h=3]Source[/b]University Medical Center of Southern Nevada, Las Vegas, Nevada.</p><p></p><p>[h=3]Abstract[/b][h=4]PURPOSE:[/b]Men with prostate cancer receiving androgen deprivation therapy (ADT) are at increased risk for decreased bone mineral density (BMD). This study evaluates the relationship between self-reported daily activity, endurance and resistance exercise, and BMD measured by dual-energy x-ray absorptiometry (DEXA) in prostate cancer patients receiving ADT.</p><p>[h=4]DATA SOURCES:[/b]We recruited 96 men treated with ADT for &#8805;9 months from urology and cancer practices. The Canadian Fitness Survey assessed daily activity and exercise. Data on demographic and lifestyle characteristics and calcium and vitamin D supplementation were collected. Blood was collected for analysis of 25-OH vitamin D. A DEXA scan was performed.</p><p>[h=4]CONCLUSIONS:[/b]A positive association between endurance exercise and DEXA T-scores of the hip was shown. Regression analysis showed endurance exercise of medium to heavy intensity (measured as energy expenditure in MET-hours/week) was associated with T-scores of the hip (&#946; = 0.048; 95% CI 0.003, 0.112; p = .040) but not with spinal T-scores after controlling for age, body mass index, and alcohol use.</p><p>[h=4]IMPLICATIONS FOR PRACTICE:[/b]Findings are cross-sectional, but if confirmed in prospective studies suggest that increased endurance exercise is a practical measure nurse practitioners can institute to prevent low bone density in the hip of men treated with ADT.</p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 2597, member: 3"] Many men with prostate cancer receive androgen suppression therapy to decrease their testosterone to castrate levels. Those men what a lot of quality of life issues and body changes. They loss sex drive, have ED, loss bone density and lean mass, and gain fat. It is a very difficult patient population after cancer is treated since most doctors fear that giving them testosterone will fuel any potentially hidden cancer cells. This study shows that exercise may at least improve some of the bone mass lost in those men.[URL="http://www.ncbi.nlm.nih.gov/pubmed/24170604#"] J Am Assoc Nurse Pract.[/URL] 2013 Aug 27. doi: 10.1002/2327-6924.12066. [Epub ahead of print] [b]Self-reported exercise and bone mineral density in prostate cancer patients receiving androgen deprivation therapy.[/b][URL="http://www.ncbi.nlm.nih.gov/pubmed?term=Mennen-Winchell%20LJ%5BAuthor%5D&cauthor=true&cauthor_uid=24170604"]Mennen-Winchell LJ[/URL], [URL="http://www.ncbi.nlm.nih.gov/pubmed?term=Grigoriev%20V%5BAuthor%5D&cauthor=true&cauthor_uid=24170604"]Grigoriev V[/URL], [URL="http://www.ncbi.nlm.nih.gov/pubmed?term=Alpert%20P%5BAuthor%5D&cauthor=true&cauthor_uid=24170604"]Alpert P[/URL], [URL="http://www.ncbi.nlm.nih.gov/pubmed?term=Dos%20Santos%20H%5BAuthor%5D&cauthor=true&cauthor_uid=24170604"]Dos Santos H[/URL], [URL="http://www.ncbi.nlm.nih.gov/pubmed?term=Tonstad%20S%5BAuthor%5D&cauthor=true&cauthor_uid=24170604"]Tonstad S[/URL]. [h=3]Source[/b]University Medical Center of Southern Nevada, Las Vegas, Nevada. [h=3]Abstract[/b][h=4]PURPOSE:[/b]Men with prostate cancer receiving androgen deprivation therapy (ADT) are at increased risk for decreased bone mineral density (BMD). This study evaluates the relationship between self-reported daily activity, endurance and resistance exercise, and BMD measured by dual-energy x-ray absorptiometry (DEXA) in prostate cancer patients receiving ADT. [h=4]DATA SOURCES:[/b]We recruited 96 men treated with ADT for ≥9 months from urology and cancer practices. The Canadian Fitness Survey assessed daily activity and exercise. Data on demographic and lifestyle characteristics and calcium and vitamin D supplementation were collected. Blood was collected for analysis of 25-OH vitamin D. A DEXA scan was performed. [h=4]CONCLUSIONS:[/b]A positive association between endurance exercise and DEXA T-scores of the hip was shown. Regression analysis showed endurance exercise of medium to heavy intensity (measured as energy expenditure in MET-hours/week) was associated with T-scores of the hip (β = 0.048; 95% CI 0.003, 0.112; p = .040) but not with spinal T-scores after controlling for age, body mass index, and alcohol use. [h=4]IMPLICATIONS FOR PRACTICE:[/b]Findings are cross-sectional, but if confirmed in prospective studies suggest that increased endurance exercise is a practical measure nurse practitioners can institute to prevent low bone density in the hip of men treated with ADT. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Exercise Improves Hip Bone but Not Lumbar Bone Density in Chemically Castrated Men
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