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General Health & Fitness
Health & Wellness
Evaluation of the Male with Erectile Dysfunction
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<blockquote data-quote="madman" data-source="post: 274982" data-attributes="member: 13851"><p><em><strong>*<u>Erectile dysfunction can be considered both a marker of endothelial dysfunction, involving the nitric acid-dependent vasodilation pathway, as well as a marker of atherosclerosis affecting penile blood flow</u>. The manifestation of this dysfunction is then ED, which can be a harbinger for subclinical coronary artery disease (CAD) and a precursor for cardiovascular events [9].</strong></em></p><p><em><strong></strong></em></p><p><em><strong>*As we have emphasized, the coexistence of ED and cardiovascular disease is strong, often in men without any overt symptoms of angina or shortness of breath with exercise. <u>All men presenting with a complaint of ED should be regarded as at potential risk for significant cardiovascular disease, therefore these patients should be particularly screened (Figure 37.1)</u>. <u>New onset ED may precede symptoms of CAD, particularly in younger men as vascular ED and CAD may be manifestations of the same disease</u>. <u>A flow-limiting arterial plaque is more likely to manifest itself earlier in the penile caversonal arteries that are approximately 1–2 mm, while coronary arteries are 3–4 mm in diameter, and therefore more likely to manifest symptoms of a flow-limiting plaque much later in the disease course</u> [28]. Early identification and treatment may prevent future cardiac events [29].</strong></em></p></blockquote><p></p>
[QUOTE="madman, post: 274982, member: 13851"] [I][B]*[U]Erectile dysfunction can be considered both a marker of endothelial dysfunction, involving the nitric acid-dependent vasodilation pathway, as well as a marker of atherosclerosis affecting penile blood flow[/U]. The manifestation of this dysfunction is then ED, which can be a harbinger for subclinical coronary artery disease (CAD) and a precursor for cardiovascular events [9]. *As we have emphasized, the coexistence of ED and cardiovascular disease is strong, often in men without any overt symptoms of angina or shortness of breath with exercise. [U]All men presenting with a complaint of ED should be regarded as at potential risk for significant cardiovascular disease, therefore these patients should be particularly screened (Figure 37.1)[/U]. [U]New onset ED may precede symptoms of CAD, particularly in younger men as vascular ED and CAD may be manifestations of the same disease[/U]. [U]A flow-limiting arterial plaque is more likely to manifest itself earlier in the penile caversonal arteries that are approximately 1–2 mm, while coronary arteries are 3–4 mm in diameter, and therefore more likely to manifest symptoms of a flow-limiting plaque much later in the disease course[/U] [28]. Early identification and treatment may prevent future cardiac events [29].[/B][/I] [/QUOTE]
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Evaluation of the Male with Erectile Dysfunction
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