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That is interesting. I went on a combination of Testopel pellets and compounded pellets six weeks ago (my insurance company only covers six Testopel pellets). I reviewed my five-week test results with my urologist today. My total testosterone was 617, which is over 200 points higher than it was on topical testosterone. My E2 was 36.1. My doc said that he usually does not do anything to control E2 until it is over 50 unless a guy is symptomatic. I am completely side-effect free and feel the best I have since my early thirties (my girlfriend has a high libido, so she is loving it). I know that pellet therapy has been controversial on this site, but the difference in how I feel on pellets versus I how I felt on topical testosterone is like the difference between night and day. I no longer have the bloating and night sweats thing going on. There were nights where I soaked the mattress pad on my bed when I was on topical testosterone. I have to have another blood test in five weeks to see if the number of pellets needs to be tweaked.
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