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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
EOD vs twice weekly Sustanon fluctuation could be the key
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<blockquote data-quote="madman" data-source="post: 186996" data-attributes="member: 13851"><p>This is the main issue in many cases when injecting once weekly as the peak will be very high 8-12 hrs post-injection, levels will be elevated a few days after, and by weeks end will be much lower sometimes resulting in too low of a trough depending on the dose, TT/SHBG.</p><p></p><p>This can have a negative impact on energy/mood/libido/erectile function/recovery.</p><p></p><p>Testosterone levels will not be as stable throughout the week as when injecting daily or EOD.</p><p></p><p>Some men do like the wide swing in hormones from injecting higher doses once weekly but for many, it can cause issues.</p><p></p><p>You are most likely hitting a true peak (8-12 hr post-injection) of 1586+ ng/dL (+55 nmol/L) and as you can see your trough although not true trough as you tested 12-24 hrs before your injection was much lower 721 ng/dL (25 nmol/L).</p><p></p><p>Mind you I would be more concerned with the FT level and depending on your TT/ SHBG it may very well be high at the trough (weeks end).</p><p></p><p>If it is what works best for you then stick with it.</p><p></p><p>Keep in mind that it is doubtful you will ever truly mimic the honeymoon period one may experience when starting trt or tweaking protocol (dose/injection frequency).</p><p></p><p>The surge in dopamine and rise in androgen levels is temporary and once levels stabilize the body will eventually adapt to those new levels (become the new norm).</p><p></p><p>Let alone we are in no way mimicking the natural 24 hr circadian rhythm of a healthy young male.</p><p></p><p>Even with once-weekly injections, you are only going to experience a surge in levels for a few days every week.</p><p></p><p>Much more involved than just the dose/injection frequency as the hpta is shut down which may very well have long term consequences on overall health/well-being.</p><p></p><p></p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/is-hcg-is-still-needed.21525/#post-186515[/URL]</p><p></p><p></p><p><strong><em><span style="color: rgb(184, 49, 47)">*</span>The documented differences in steroid profiles on testosterone replacement in hypogonadal males with absent or severely reduced endogenous LH and FSH secretion may <span style="color: rgb(184, 49, 47)">have long term consequences for health and wellbeing. Specifically, body composition, bone health, glucose, and lipid metabolism, salt and water balance, cognition, mood, sleep, and sexual function could be affected.</span></em></strong></p></blockquote><p></p>
[QUOTE="madman, post: 186996, member: 13851"] This is the main issue in many cases when injecting once weekly as the peak will be very high 8-12 hrs post-injection, levels will be elevated a few days after, and by weeks end will be much lower sometimes resulting in too low of a trough depending on the dose, TT/SHBG. This can have a negative impact on energy/mood/libido/erectile function/recovery. Testosterone levels will not be as stable throughout the week as when injecting daily or EOD. Some men do like the wide swing in hormones from injecting higher doses once weekly but for many, it can cause issues. You are most likely hitting a true peak (8-12 hr post-injection) of 1586+ ng/dL (+55 nmol/L) and as you can see your trough although not true trough as you tested 12-24 hrs before your injection was much lower 721 ng/dL (25 nmol/L). Mind you I would be more concerned with the FT level and depending on your TT/ SHBG it may very well be high at the trough (weeks end). If it is what works best for you then stick with it. Keep in mind that it is doubtful you will ever truly mimic the honeymoon period one may experience when starting trt or tweaking protocol (dose/injection frequency). The surge in dopamine and rise in androgen levels is temporary and once levels stabilize the body will eventually adapt to those new levels (become the new norm). Let alone we are in no way mimicking the natural 24 hr circadian rhythm of a healthy young male. Even with once-weekly injections, you are only going to experience a surge in levels for a few days every week. Much more involved than just the dose/injection frequency as the hpta is shut down which may very well have long term consequences on overall health/well-being. [URL unfurl="true"]https://www.excelmale.com/forum/threads/is-hcg-is-still-needed.21525/#post-186515[/URL] [B][I][COLOR=rgb(184, 49, 47)]*[/COLOR]The documented differences in steroid profiles on testosterone replacement in hypogonadal males with absent or severely reduced endogenous LH and FSH secretion may [COLOR=rgb(184, 49, 47)]have long term consequences for health and wellbeing. Specifically, body composition, bone health, glucose, and lipid metabolism, salt and water balance, cognition, mood, sleep, and sexual function could be affected.[/COLOR][/I][/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
EOD vs twice weekly Sustanon fluctuation could be the key
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