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Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
Enclomiphene - Dose / Frequency / Follow Up Labs?
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<blockquote data-quote="aneuman" data-source="post: 225556" data-attributes="member: 43264"><p><h4>ResearchIt,</h4><p></p><p>I'm 59. I understand exactly where you're coming from, as I experience similar symptoms. I've been on enclomiphene 12.5mg every day sin January (6 months approx) and it started working very quickly. My T levels went from 300 to 780 in a less than month, however, sorry to say that none of the symptoms you mentioned have improved. </p><p></p><p>Enclomiphene is "Selective Estrogen Receptor Modulator", which means that it selectively blocks certain estrogen receptor inhibiting negative feedback and the pituitary/hypothalamus level, thus increasing the release of gonadotropins (LH and FSH) ergo instructing the testicles to produce more testosterone. Problem is, what other receptors does it block? What happens when these receptors are blocked? What is the effect of blocking those receptors in the Hypothalamus/Pituitary for a long time? What happens when LH and FSH are abnormally elevated for a long time? The human body has the nasty tendency to find homeostasis (balance) and we don't know what the body will do with such imbalance and and what mechanisms it will use to correct it. I'm not sure I'd recommend you going that route given your T levels are adequately healthy, but I've been where you are and I totally understand the need to do something. There may be other reasons in your case why this is happening, and you will get many suggestions in this forum, 99% of which won't work. You will be asked for blood work results and offer to lower prolactin, increase dopamine, lower estradiol, increase estradiol, bring up DHEA, stay away from DHEA, take zinc, but be careful with copper, try T-Cypionate IM, no, sub-q, progesterone creams... bottom line, be careful. Feel free to try, but understand the risks involved. Wouldn't hurt to visit and honest and knowledgeable andrologist who's not running a pill mill, if such thing exists.</p><p></p><p>The only thing I can really say was a fountain of youth in every sense was HCG. Last year I started 2000 UI/week and in 3 weeks I was like 30 years old again. Orgasm, libido, erection, nocturnal erections, desire, optimistic outlook, sense of wellbeing, confidence, fuller and more sensitive penis, and yes, big balls <img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite1" alt=":)" title="Smile :)" loading="lazy" data-shortname=":)" /> </p><p></p><p>Unfortunately, after that honey moon which lasted about 3 or 4 weeks, things started going downhill fast, and I ended up worse off than I started. Literally, my starting T was 492, after 3 months of HCG it was 305. I felt drained. It coincided with the FDA ban on compounded HCG and my doctor switched me to Enclomiphene.</p><p></p><p>The only changes I have observed while on enclomiphene are, 1) I'm less moody, more calmed and collected and overreact less to disagreements, more accepting and also more willing to do things around the house and exercise (although there's some evidence these effects are starting to wear off) and, 2) my nipples (not the areola) are bigger and frequently hard, there's no mass under the areola, so it may or may not be gyno. </p><p></p><p>I have blood work scheduled soon and I can update the thread if requested. I also changed doctors since my previous one, although well-known and highly regarded as a top andrologist (even in this forum) does not seem to pay much attention to symptoms or even blood work (he only ordered what I asked him to do when I asked him to do it) and seemed to have the solution before he heard what the problem was, so I'll see how it goes with the new one.</p></blockquote><p></p>
[QUOTE="aneuman, post: 225556, member: 43264"] [HEADING=3]ResearchIt,[/HEADING] I'm 59. I understand exactly where you're coming from, as I experience similar symptoms. I've been on enclomiphene 12.5mg every day sin January (6 months approx) and it started working very quickly. My T levels went from 300 to 780 in a less than month, however, sorry to say that none of the symptoms you mentioned have improved. Enclomiphene is "Selective Estrogen Receptor Modulator", which means that it selectively blocks certain estrogen receptor inhibiting negative feedback and the pituitary/hypothalamus level, thus increasing the release of gonadotropins (LH and FSH) ergo instructing the testicles to produce more testosterone. Problem is, what other receptors does it block? What happens when these receptors are blocked? What is the effect of blocking those receptors in the Hypothalamus/Pituitary for a long time? What happens when LH and FSH are abnormally elevated for a long time? The human body has the nasty tendency to find homeostasis (balance) and we don't know what the body will do with such imbalance and and what mechanisms it will use to correct it. I'm not sure I'd recommend you going that route given your T levels are adequately healthy, but I've been where you are and I totally understand the need to do something. There may be other reasons in your case why this is happening, and you will get many suggestions in this forum, 99% of which won't work. You will be asked for blood work results and offer to lower prolactin, increase dopamine, lower estradiol, increase estradiol, bring up DHEA, stay away from DHEA, take zinc, but be careful with copper, try T-Cypionate IM, no, sub-q, progesterone creams... bottom line, be careful. Feel free to try, but understand the risks involved. Wouldn't hurt to visit and honest and knowledgeable andrologist who's not running a pill mill, if such thing exists. The only thing I can really say was a fountain of youth in every sense was HCG. Last year I started 2000 UI/week and in 3 weeks I was like 30 years old again. Orgasm, libido, erection, nocturnal erections, desire, optimistic outlook, sense of wellbeing, confidence, fuller and more sensitive penis, and yes, big balls :) Unfortunately, after that honey moon which lasted about 3 or 4 weeks, things started going downhill fast, and I ended up worse off than I started. Literally, my starting T was 492, after 3 months of HCG it was 305. I felt drained. It coincided with the FDA ban on compounded HCG and my doctor switched me to Enclomiphene. The only changes I have observed while on enclomiphene are, 1) I'm less moody, more calmed and collected and overreact less to disagreements, more accepting and also more willing to do things around the house and exercise (although there's some evidence these effects are starting to wear off) and, 2) my nipples (not the areola) are bigger and frequently hard, there's no mass under the areola, so it may or may not be gyno. I have blood work scheduled soon and I can update the thread if requested. I also changed doctors since my previous one, although well-known and highly regarded as a top andrologist (even in this forum) does not seem to pay much attention to symptoms or even blood work (he only ordered what I asked him to do when I asked him to do it) and seemed to have the solution before he heard what the problem was, so I'll see how it goes with the new one. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Clomid for PCT, fertility or low T
Enclomiphene - Dose / Frequency / Follow Up Labs?
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