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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
E2 test
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<blockquote data-quote="MarkM" data-source="post: 113702"><p>Typically an E2 on the non-sensitive test, Roche ECLIA, coming in at 30 could easily mean you would come in low on the Estradiol Sensitive test, LC/MS/MS assay. Not always, but probably 95% of the time. There are individuals, including a few on this forum, that have had their non-sensitive E2 come back higher than their Estradiol Sensitive. In your case, a result of 30 on either test would not generally be considered high under any circumstance I can think of. </p><p></p><p>In my last blood work in May, my non-sensitive E2 come in at 91.0 pg/ml on a range of 7.6 - 42.6 pg/ml and my Estradiol Sensitive came in at 35.3 pg/ml on a range of 8.0 - 35.0 pg/ml. If I allowed a doctor to treat me based off the non-sensitive E2 test and result of 91.0 pg/ml I would have been prescribed 1mg or anastrozole two to three times a week. </p><p></p><p>This is why it is so important to make sure we have our estradiol tested on the Sensitive, LC/MS/MS assay. It is much more accurate for men. The Roche ECLIA is designed for women and can way overestimate the estradiol in men, as my non-sensitive test result shows. Imagine if I was really 91.0? My "little buddy" would probably turn himself inside out and I would be lactating. By the way, I take no AI.</p><p></p><p>Your question of "are they really pushing the AI too much. Like the PA not legitimately worried when my e2 was 30." I just don't think the PA had a clue what they are managing. <span style="color: #333333"><em></em></span></p><p><span style="color: #333333"><em></em></span></p><p><span style="color: #333333"><em></em></span></p></blockquote><p></p>
[QUOTE="MarkM, post: 113702"] Typically an E2 on the non-sensitive test, Roche ECLIA, coming in at 30 could easily mean you would come in low on the Estradiol Sensitive test, LC/MS/MS assay. Not always, but probably 95% of the time. There are individuals, including a few on this forum, that have had their non-sensitive E2 come back higher than their Estradiol Sensitive. In your case, a result of 30 on either test would not generally be considered high under any circumstance I can think of. In my last blood work in May, my non-sensitive E2 come in at 91.0 pg/ml on a range of 7.6 - 42.6 pg/ml and my Estradiol Sensitive came in at 35.3 pg/ml on a range of 8.0 - 35.0 pg/ml. If I allowed a doctor to treat me based off the non-sensitive E2 test and result of 91.0 pg/ml I would have been prescribed 1mg or anastrozole two to three times a week. This is why it is so important to make sure we have our estradiol tested on the Sensitive, LC/MS/MS assay. It is much more accurate for men. The Roche ECLIA is designed for women and can way overestimate the estradiol in men, as my non-sensitive test result shows. Imagine if I was really 91.0? My "little buddy" would probably turn himself inside out and I would be lactating. By the way, I take no AI. Your question of "are they really pushing the AI too much. Like the PA not legitimately worried when my e2 was 30." I just don't think the PA had a clue what they are managing. [COLOR=#333333][I] [/I][/COLOR] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
E2 test
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