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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
E2 sweet spot, it's a ratio
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<blockquote data-quote="apsjiml" data-source="post: 168351" data-attributes="member: 12831"><p>I am not sure about ratios or anything like that but SHBG increases the half life of testosterone and estradiol. So, if shbg is elevated it would make total t and e higher . However, of course, that does not necessarily correlate with free usable estradiol . I am a little hesitant on saying what a level should be for estradiol, because that doesn't always seem to correlate well with free estradiol levels</p><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066276/" target="_blank">Sex hormone-binding globulin regulation of androgen bioactivity in vivo: validation of the free hormone hypothesis</a> </p><p></p><p><a href="https://academic.oup.com/jcem/article/91/4/1336/2843369" target="_blank">Testosterone and Estradiol among Older Men</a></p></blockquote><p></p>
[QUOTE="apsjiml, post: 168351, member: 12831"] I am not sure about ratios or anything like that but SHBG increases the half life of testosterone and estradiol. So, if shbg is elevated it would make total t and e higher . However, of course, that does not necessarily correlate with free usable estradiol . I am a little hesitant on saying what a level should be for estradiol, because that doesn't always seem to correlate well with free estradiol levels [URL="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066276/"]Sex hormone-binding globulin regulation of androgen bioactivity in vivo: validation of the free hormone hypothesis[/URL] [URL="https://academic.oup.com/jcem/article/91/4/1336/2843369"]Testosterone and Estradiol among Older Men[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
E2 sweet spot, it's a ratio
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