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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
E2 always measured at maximum - where is the average?
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<blockquote data-quote="Cataceous" data-source="post: 162856" data-attributes="member: 38109"><p>[USER=33138]@albatross[/USER] : There was a spreadsheet floating around the net called "Test and E2 Calculations V0.1.xlsx", which I may have attached. It contains some fairly detailed modeling, including the effects of AIs. With respect to exemestane, the author says "To account for the effect of an AI, this spreadsheet assumes your E2 will be linearly proportional to your aromatase enzyme level. Aromasin has a short half life, and it functions by binding to and killing your aromatase enzyme. So the model assumes Aromasin is only active right when you take it. It still keeps E2 low for ~2-3 days, while your body is producing more aromatase enzyme. (Aromasin is what reduces the column “aromatase (total)” below 100% - the other AIs only affect the unbound amount)"</p><p></p><p>I think if you play around with the spreadsheet, and/or appropriate the underlying models, you should be able to get a rough idea of what your estradiol is doing in between doses.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 162856, member: 38109"] [USER=33138]@albatross[/USER] : There was a spreadsheet floating around the net called "Test and E2 Calculations V0.1.xlsx", which I may have attached. It contains some fairly detailed modeling, including the effects of AIs. With respect to exemestane, the author says "To account for the effect of an AI, this spreadsheet assumes your E2 will be linearly proportional to your aromatase enzyme level. Aromasin has a short half life, and it functions by binding to and killing your aromatase enzyme. So the model assumes Aromasin is only active right when you take it. It still keeps E2 low for ~2-3 days, while your body is producing more aromatase enzyme. (Aromasin is what reduces the column “aromatase (total)” below 100% - the other AIs only affect the unbound amount)" I think if you play around with the spreadsheet, and/or appropriate the underlying models, you should be able to get a rough idea of what your estradiol is doing in between doses. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
E2 always measured at maximum - where is the average?
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