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SHBG is measured and a protocol is designed, it doesn't sounds like your friends doctor doesn't have any idea what he's doing and has no business prescribing testosterone. A 12 year old study below proves that injecting every 2 weeks doesn't work when the half life of the hormone you're injecting is on average 8 days depending on your SHBG. Your friend is going even longer than 2 weeks.

You should tell you friend there aren't many doctors inside insurance networks who know how to replace a man's hormones, going private is the only sane route. Most of the members who found this forum have gone private which is the only place hormone specialists practice.

Endocrinologists and urologists are the worst at TRT, it's not usually their specialty as most don't know the first thing about TRT. We have a lot of members who have gone with Defy Medical who offers telemedicine and mails everything to you and staffs doctors who have been doing TRT for decades.

https://www.excelmale.com/forum/threads/the-12-year-old-study-that-proves-testosterone-injections-every-two-weeks-fail.12771/#post88718