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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Dosage and blood work anomaly
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<blockquote data-quote="Cataceous" data-source="post: 221435" data-attributes="member: 38109"><p>It's possible that your higher dose of 140 mg/wk drove down your SHBG substantially. As you lowered the dose your SHBG recovered by varying degrees. Think of your dose of testosterone cypionate as driving free testosterone, not total testosterone. Chances are pretty good that if you had been measuring your free testosterone with an accurate method then you would see a good correlation with dose. Total testosterone should be considered as a dependent variable, the result of a complex function of free testosterone, SHBG and albumin. Total testosterone can correlate with free testosterone when the other variables are constant, but in your case SHBG is likely inversely correlated with dose, which effectively prevents a rise in total testosterone with dose.</p><p></p><p>In any case, free testosterone is more important than total; it's largely what drives your results.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 221435, member: 38109"] It's possible that your higher dose of 140 mg/wk drove down your SHBG substantially. As you lowered the dose your SHBG recovered by varying degrees. Think of your dose of testosterone cypionate as driving free testosterone, not total testosterone. Chances are pretty good that if you had been measuring your free testosterone with an accurate method then you would see a good correlation with dose. Total testosterone should be considered as a dependent variable, the result of a complex function of free testosterone, SHBG and albumin. Total testosterone can correlate with free testosterone when the other variables are constant, but in your case SHBG is likely inversely correlated with dose, which effectively prevents a rise in total testosterone with dose. In any case, free testosterone is more important than total; it's largely what drives your results. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Dosage and blood work anomaly
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