I had to google estrone as it is not normally tested in either men or women.
It appears estrone is usually higher than estrogen. Estrone is a weak estrogen.
Negatively speaking, higher levels of estrone is associated with higher risk of T2DM. But what if anything to do about it ??
And when they say associated, it means just that, not that it either causes or is caused by T2DM, they don't seem to know.
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In conclusion, estrone but not estradiol levels were associated with increased risk of incident T2DM in a cohort of community-dwelling men. Future studies should test and confirm this relationship between estrone and T2DM in older men in other populations and investigate the mediating mechanisms.
Circulating Estrone Levels Are Associated Prospectively With Diabetes Risk in Men of the Framingham Heart Study
As far as doing a therapeutic phlebotomy, I am 50/50 on it. It probably wouldn't hurt since your HCT/Hemoglobin are in a healthy range. Why would your iron levels be on the high side? Maybe try to reduce Iron levels naturally?
Vince just posted a thread on ferritin levels.
Reducing ferritin levels to lower the risk of heart attack and cancer.
Reducing ferritin levels to lower the risk of heart attack and cancer
